Comparison of the intraocular pressure-lowering effect and safety of brimonidine/timolol fixed combination and 0.5% timolol in normal-tension glaucoma patients.

Author: KimChan Yun, KimHwang Ki, KimJoon Mo, KimTae-Woo, ParkKi Ho

Paper Details 
Original Abstract of the Article :
PURPOSE: To compare the therapeutic efficacy and safety of brimonidine/timolol fixed-combination (BTFC) and 0.5% timolol ophthalmic solution in normal-tension glaucoma (NTG) patients. METHODS: This was a multi-institution, randomized, active-controlled, open-label, parallel-group study. After a ful...See full text at original site
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引用元:
https://doi.org/10.1007/s10384-015-0420-2

データ提供:米国国立医学図書館(NLM)

Brimonidine/Timolol Fixed Combination vs. Timolol: A Showdown in Normal-Tension Glaucoma

In the realm of [normal-tension glaucoma (NTG)], where delicate eye pressure regulation is key, researchers sought to find the most effective treatment. This study presents a head-to-head comparison of [brimonidine/timolol fixed-combination (BTFC) and 0.5% timolol ophthalmic solution], two commonly used medications. The researchers embarked on a clinical trial, akin to a desert expedition, to meticulously assess the efficacy and safety of these drugs.

BTFC Emerges as a Clear Winner

The study reveals that BTFC is a more potent IOP-lowering agent compared to 0.5% timolol. A significantly higher percentage of patients in the BTFC group experienced a greater than 20% reduction in IOP after both 4 and 12 weeks. This suggests that BTFC may be a more effective option for managing NTG.

Keeping NTG at Bay: A New Weapon in the Arsenal

The findings of this study could lead to improved management of NTG, a condition that affects millions worldwide. Just as a desert traveler relies on a reliable compass, individuals with NTG need effective treatments to navigate their journey towards healthy vision.

Dr. Camel's Conclusion

This research serves as a reminder that in the field of medicine, like a desert landscape, there are always new discoveries to be made. BTFC emerges as a potential game-changer for NTG, providing a new weapon in the fight against this debilitating eye condition.

Date :
  1. Date Completed 2016-10-14
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26578422

DOI: Digital Object Identifier

10.1007/s10384-015-0420-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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