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Cefixime versus amoxicillin/clavulanic acid in lower respiratory tract infections.

Author: BeumerH M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cefixime twice daily is comparable in safety and efficacy to amoxicillin/clavulanic acid thrice daily in treating acute bronchitis. In a double-blind study of 60 patients, both treatments showed similar bacteriological eradication rates (54% for cefixime and 52% for amoxicillin/clavulanic acid) and positive clinical response rates (71% for cefixime and 74% for amoxicillin/clavulanic acid). No side effects or significant adverse laboratory changes were observed in either group.
Paper Details　
Original Abstract of the Article :
Sixty patients with lower respiratory tract infections, mainly acute bronchitis were treated for 14 days with either cefixime 200 mg twice daily (plus placebo once daily) or amoxicillin/clavulanic acid 500 mg/125 mg thrice daily in a double-blind manner. The sputum cultures indicated that all isolat...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2663735

データ提供：米国国立医学図書館（NLM）

Cefixime vs. Amoxicillin/Clavulanic Acid: A Duel in the Desert

This study compares the effectiveness of cefixime and amoxicillin/clavulanic acid for treating lower respiratory tract infections (LRTIs). LRTIs are like unwelcome guests in your lungs, causing coughs, wheezing, and shortness of breath. This study uses a double-blind approach to compare the two treatments, like a desert race where the competitors don’t know which camel is leading the pack.

Two Powerful Treatments Go Head-to-Head

Researchers found that both cefixime and amoxicillin/clavulanic acid were effective in treating LRTIs, with similar eradication rates and clinical response. It's like having two equally strong camels in a race, both able to reach the finish line.

Both Safe and Effective

The study also confirmed that both treatments are well-tolerated, with no significant side effects. It’s like having a smooth desert journey, free from any bumps in the road.

Dr.Camel's Conclusion

This study shows that both cefixime and amoxicillin/clavulanic acid are effective options for treating LRTIs. It’s like having two reliable camels to carry you through the desert of illness.

Date :
  1. Date Completed 1989-08-17
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2663735

DOI: Digital Object Identifier

2663735

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・Side Effects of cefixime
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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