Side Effects of cefixime: A Synthesis of Findings from 32 Studies

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This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Side Effects of cefixime: A Synthesis of Findings from 32 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

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This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Main Research Findings

Cefixime has been shown in multiple studies to be effective in treating bacterial infections in children. 21 , 22 , 7 , 6 , 3 , 23 , 30 , 11 Cefixime has been shown to be effective against many bacteria, particularly Streptococcus pneumoniae, Haemophilus influenzae and Streptococcus pyogenes. 22 , 6 , 20 Cefixime has also been shown to be effective in treating urinary tract infections. 16 , 26 , 17 , 28 Cefixime also has the advantage of having fewer side effects compared to other antibiotics. 13 Cefixime has been shown to be safe for administration to children. 21 , 7 , 6 , 3 , 23 , 30 , 11 , 18 However, cefixime is not safe for all patients to take. You should talk to your doctor before taking cefixime.

Reason for Side Effects

Side effects of cefixime can be caused by the mechanism of action of the drug, as well as the patient's constitution and physical condition. Cefixime exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls. When the synthesis of bacterial cell walls is inhibited, bacteria die due to rupture of the cell membrane. The side effects of cefixime occur when the drug affects cells other than bacteria. Cefixime tends to affect digestive system cells, making digestive system side effects more likely. Cefixime is also metabolized in the liver, so it can affect the liver. The side effects of cefixime also vary depending on the patient's constitution and physical condition. Elderly people and patients with impaired kidney function are more likely to experience side effects.

Common Side Effects

Gastrointestinal

The most common side effect of cefixime is gastrointestinal symptoms. Cefixime tends to affect digestive system cells, which can cause symptoms such as diarrhea, soft stools, abdominal pain, nausea and vomiting. 21 , 7 , 3 , 23 , 30 , 11 , 19 , 18 , 20 , 12 , 24 , 5 , 14 , 9 These gastrointestinal side effects often improve when you stop taking cefixime.

Liver

Cefixime is metabolized in the liver, so it has the potential to affect the liver. Taking cefixime can cause elevated liver function test values such as GOT and GPT. 21 , 22 , 11 However, elevated liver function test values usually return to normal when you stop taking cefixime.

Blood

Cefixime can also affect the blood. Taking cefixime can cause symptoms such as leukopenia and thrombocytopenia. 3 , 30 Leukopenia and thrombocytopenia can make you more susceptible to infections or make you more likely to bleed. These side effects usually go away when you stop taking cefixime.

Allergy

Cefixime can cause allergic reactions. Taking cefixime can cause symptoms such as rash, itching, and difficulty breathing. Allergic reactions can be life-threatening if they become severe. If you have an allergic reaction, stop taking cefixime immediately and consult your doctor.

Countermeasures for Side Effects

Gastrointestinal

To reduce gastrointestinal side effects, it is effective to take cefixime after meals or with milk. Cefixime is more likely to cause gastrointestinal side effects when taken on an empty stomach. Taking it after meals or with milk can reduce the burden on the digestive system. If you experience symptoms such as diarrhea, drink plenty of fluids and take antidiarrheal medications, etc.

Liver

If your liver function is impaired, you should avoid taking cefixime. Talk to your doctor about your liver function before taking cefixime. If your liver function test values are elevated, you need to stop taking cefixime.

Blood

If you have any blood abnormalities, you should stop taking cefixime. Talk to your doctor about blood tests before taking cefixime.

Allergy

Cefixime can cause allergic reactions. Talk to your doctor about your history of allergies before taking cefixime. If you have an allergic reaction, stop taking cefixime immediately and consult your doctor.

Comparison between Studies

Common Points of Studies

Cefixime has been shown in multiple studies to be effective in treating bacterial infections in children. 21 , 22 , 7 , 6 , 3 , 23 , 30 , 11 Cefixime also has the advantage of having fewer side effects compared to other antibiotics. 13 Cefixime has been shown to be safe for administration to children. 21 , 7 , 6 , 3 , 23 , 30 , 11 , 18

Differences between Studies

There are differences in the frequency and types of side effects reported in studies on cefixime. For example, some studies report frequent gastrointestinal side effects, while others report fewer gastrointestinal side effects. Some studies also report elevated liver function test values, while others do not. These differences are likely due to differences in the age and condition of the patients in the studies, the dosage of cefixime, and the study methods.

Precautions for Real-Life Applications

Cefixime has been shown to be an effective drug for treating bacterial infections in children, but it is not safe for all patients. Talk to your doctor before taking cefixime. Also, if you experience side effects while taking cefixime, stop taking cefixime immediately and consult your doctor.

Limitations of Current Research

Research on the side effects of cefixime is still insufficient. In particular, there is still much that is not known about long-term side effects. More research on the long-term side effects of cefixime is needed.

Future Research Directions

Research on the side effects of cefixime needs to be further advanced. In particular, research on long-term side effects and research to reduce the side effects of cefixime is needed. Research to clarify individual differences in side effects to cefixime is also needed.

Conclusion

Cefixime has been shown to be an effective drug for treating bacterial infections in children. Cefixime also has the advantage of having fewer side effects compared to other antibiotics. However, cefixime is not safe for all patients to take. Talk to your doctor before taking cefixime. Also, if you experience side effects while taking cefixime, stop taking cefixime immediately and consult your doctor.

Keywords
Benefit Keywords
Respiratory tract infection treatment
1
Cholecystectomy infection prophylaxis
2
Bacterial infection treatment
Effective against various bacteria
Safe for children
3
Effective against Pseudomonas aeruginosa
Treat severe infections
4
Cefixime effectiveness
Respiratory infection treatment
5
Bacterial infection treatment
6
Bacterial infection treatment
Safe for children
7
Cefixime effective
S. typhi treatment
8
Bronchitis treatment
9
Treats sinusitis
10
Bacterial infection treatment
Safe for children
11
Respiratory infection improvement
12
Lower respiratory tract infection treatment
14
Urinary tract infection relief
15
UTI treatment
16
Effective treatment for pyelonephritis
17
Acute otitis media treatment
Less frequent dosing
18
Effective otitis media treatment
19
Respiratory tract infection treatment
20
Bacterial infection treatment
Safe for children
21
Bacterial infection treatment
Safe and effective
22
Bacterial infection treatment
Effective against various bacteria
Well tolerated
23
Sinusitis improvement
24
UTIs treatment
26
Cefixime efficacy
27
Cystitis treatment
Excellent efficacy
Satisfactory treatment
28
Safe and effective treatment
29
Safe for children
Tonsillitis treatment
UTI treatment
30
Respiratory infection improvement
31
Cefixime effectiveness
ENT infection treatment
32
Risk Keywords
Eosinophilia
3
Gastrointestinal side effects
Skin eruption
4
Gastrointestinal reactions
5
None mentioned
6
Eosinophilia
Soft stool
7
Gastrointestinal side effects
10
Diarrhea
Elevated liver enzymes
Eosinophilia
Soft stool
11
Diarrhea
Nausea
Vomiting
12
Drug hypersensitivity
Gastrointestinal side effects
13
Mild side effects
15
Vomiting
16
Gastrointestinal side effects
18
Side effects
19
Diarrhea
Loose stool
20
Elevated liver enzymes
21
Eosinophilia
Liver enzyme elevation
22
None mentioned
23
Gastrointestinal side effects
24
Sulfonamide side effects
25
Side effects
26
Heaviness in the head
28
Diarrhea
Mild side effects
29
Elevated platelet counts
30
Diarrhea
Epigastric pain
31
Minor abdominal discomfort
32
Literature analysis of 32 papers
Positive Content
32
Neutral Content
0
Negative Content
0
Article Type
4
0
0
1
32
1.

Safety and efficacy of cefixime in treatment of respiratory tract infections in Germany.

Author: HausenT, WeidlichG, SchmittJ

Respiratory tract infection treatment

Cefixime was highly effective in treating respiratory tract infections in adults and children, with low incidence of side effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

3.

[Fundamental and clinical studies on cefixime in pediatric field].

Author: MiyazakiM, KidaK, MatsudaH, MuraseM

Bacterial infection treatment
Effective against various bacteria
Safe for children
Eosinophilia

Cefixime (CFIX) was effective in treating infections in 19 children, with a 100% effectiveness rate. The study found that CFIX was safe and effective with no significant side effects.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

4.

[Clinical evaluation of imipenem/cilastatin sodium and fosfomycin as second-line combination chemotherapy in severe infections associated with hematologic disorders].

Author: TsudaS, KuzuyamaY, NakaiH, SeriuT, TakashimaT, TanakaS, HoriikeS, TaniwakiM, MisawaS, KashimaK

Effective against Pseudomonas aeruginosa
Treat severe infections
Gastrointestinal side effects
Skin eruption

Imipenem/cilastatin sodium (IPM/CS) in combination with fosfomycin (FOM) is effective as a second-line chemotherapy for severe infections in patients with hematologic disorders.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

5.

[Comparative study of 2 dosage regimens of cefixime in the treatment of otorhinolaryngeal or bronchial infections].

Author: BoudignatO, ZylbertrestR, RocheG

Cefixime effectiveness
Respiratory infection treatment
Gastrointestinal reactions

Cefixime was effective and well-tolerated in treating upper and lower respiratory tract infections, with no significant difference in efficacy or safety between single and divided doses.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Language : French

6.

[Fundamental and clinical studies on cefixime in pediatrics].

Author: IwaiN, ShibataM, MizoguchiF, NakamuraH, KatayamaM

Bacterial infection treatment
None mentioned

Cefixime (CFIX) showed good antibacterial activity against various clinical isolates. The study found that CFIX was effective in treating infection in pediatric patients with a 92.3% effectiveness rate.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

7.

[Clinical experience with cefixime in the pediatric field].

Author: AiharaR, KobashiH, NishiokaA, OharaK, OkamotoT

Bacterial infection treatment
Safe for children
Eosinophilia
Soft stool

Cefixime (CFIX) was effective in treating acute bacterial infections in children with a good to excellent clinical response in 23 out of 25 patients.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

8.

Cefixime in the treatment of enteric fever in children.

Author: GirgisN I, KilpatrickM E, FaridZ, SultanY, PodgoreJ K

Cefixime effective
S. typhi treatment

Cefixime is an effective oral treatment for Salmonella typhi septicemia, including strains resistant to multiple antibiotics. In a study of 50 children, cefixime resulted in rapid clinical and bacteriological cure.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Language : English

9.

Betalactam therapy and intestinal flora.

Author: NovelliA, MazzeiT, FallaniS, DeiR, CassettaM I, ContiS

Bronchitis treatment

Cefetamet-pivoxil (CET) had a minimal impact on normal human intestinal flora compared to cefixime (CFX) and cefuroxime axetil (CA), which significantly affected Enterobacteriaceae and clostridia. CFX and CA also led to an increase in enterococci and the appearance of Salmonella spp. and Clostridium difficile in some cases.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

10.

Evaluation of cefixime in the treatment of bacterial maxillary sinusitis.

Author: MatthewsB L, KohutR I, EdelsteinD R, RybakL P, RappM, McCaffreyT V, KimmelmanC P, ParnesS M, MarinaccioA T, KohlbrennerV M

Treats sinusitis
Gastrointestinal side effects

Cefixime, an oral third-generation cephalosporin, was effective in treating bacterial sinus infections in 118 adult patients. It was well tolerated, with the most common side effect being diarrhea.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

11.

[Fundamental and clinical studies of cefixime granules in pediatrics].

Author: SunakawaK, SaitoN, IshizukaY, IwataS, KumagaiN, YokotaT, AsaishiT, KusanoS, SatoY, KusumotoY

Bacterial infection treatment
Safe for children
Diarrhea
Elevated liver enzymes
Eosinophilia
Soft stool

Cefixime (CFIX) granules were effective in treating bacterial infections in children. The clinical response rate was 88%, and the bacteriological eradication rate was 87.5%.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

12.

[Effectiveness and tolerance of cefixime in bacterial infections in the ENT area].

Author: TheopoldM, BennerU, BauernfeindA

Respiratory infection improvement
Diarrhea
Nausea
Vomiting

Cefixime was effective in treating 29 patients with infections, with an overall efficacy rate of 100%. It was well-tolerated, with only 27.6% of patients experiencing mild side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

13.

Safety profile of cefixime.

Author: TallyF P, DesjardinsR E, McCarthyE F, CartwrightK

Drug hypersensitivity
Gastrointestinal side effects

Cefixime was found to be safe and effective in treating urinary tract and respiratory tract infections in 2190 patients (1575 adults and 615 children). The most common side effect was gastrointestinal intolerance.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

14.

Cefixime versus amoxicillin/clavulanic acid in lower respiratory tract infections.

Author: BeumerH M

Lower respiratory tract infection treatment

Cefixime twice daily is comparable in safety and efficacy to amoxicillin/clavulanic acid thrice daily in treating acute bronchitis. In a double-blind study of 60 patients, both treatments showed similar bacteriological eradication rates (54% for cefixime and 52% for amoxicillin/clavulanic acid) and positive clinical response rates (71% for cefixime and 74% for amoxicillin/clavulanic acid). No side effects or significant adverse laboratory changes were observed in either group.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

15.

Once daily cefixime compared with twice daily trimethoprim/sulfamethoxazole for treatment of urinary tract infection in infants and children.

Author: DaganR, EinhornM, LangR, PomeranzA, WolachB, MironD, RazR, WeinstockA, SteinbergerJ, WeintraubA

Urinary tract infection relief
Mild side effects

Cefixime administered once daily was as safe and effective as TMP/SMX administered twice daily in treating acute uncomplicated urinary tract infection in children. Both groups had similar recovery rates and side effects were mild.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

16.

[Effectiveness and tolerance of cefixime in bacterial urinary tract infections in patients with myelomeningocele].

Author: CarstensC, HostalekU

UTI treatment
Vomiting

Cefixime is a cephalosporin antibiotic that is effective and well tolerated in treating complicated urinary tract infections in patients with myelomeningocele.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

17.

Evaluation of the efficacy and tolerance of a short 7 day third-generation cephalosporin treatment in the management of acute pyelonephritis in young women in the emergency department.

Author: MoustafaF, NguyenG, MathevonT, BaudO, Saint-DenisJ, DublanchetN, PereiraB, ShinjoC, RomaszkoJ P, DopeuxL, DutheilF, SchmidtJ

Effective treatment for pyelonephritis

This study investigated the efficiency and tolerance of a short 7-day treatment with third-generation cephalosporins (3GC) in uncomplicated acute pyelonephritis in women.

Clinical StudyResearch involving human participants to assess the safety, efficacy, and effects of an intervention/treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

18.

A general practice comparative study of a new third-generation oral cephalosporin, cefixime, with amoxycillin in the treatment of acute paediatric otitis media.

Author: LeighA P, RobinsonD, MillarE D

Acute otitis media treatment
Less frequent dosing
Gastrointestinal side effects

Cefixime was a safe and effective alternative to amoxycillin in treating acute otitis media in children, with a 95% favorable clinical response rate.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

19.

[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children].

Author: BabaS, KinoshitaH, MoriY, SuzukiK, ShimadaJ, KawamuraS, OnishiS, UedaR, KobayashiK, ItohY

Effective otitis media treatment
Side effects

Cefixime (CFIX) was as effective as cefaclor (CCL) in treating acute suppurative otitis media in children. CFIX was significantly superior to CCL in eradicating bacteria (97.1% vs 90.3%, P<.05) and improving individual symptoms. Both drugs were well tolerated.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

21.

[Fundamental and clinical studies on cefixime in pediatrics].

Author: KurashigeT, MoritaH, ArakiK, OguraH, MoriokaN, KitamuraI

Bacterial infection treatment
Safe for children
Elevated liver enzymes

Cefixime (CFIX) fine granules were effective in treating bacterial infections in children. The study found that CFIX was safe and effective with a 100% effectiveness rate.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

23.

[Fundamental and clinical studies on cefixime (5% granules) in the pediatric field].

Author: ToyonagaY, SugitaM, NakamuraH, JohK, TakahashiT, KurosuY, HoriM

Bacterial infection treatment
Effective against various bacteria
Well tolerated
None mentioned

Cefixime (CFIX) 5% granules showed greater activity than other antibiotics against several Gram-negative bacteria. The study found that CFIX was effective in treating infections in 33 patients with a 97.0% effectiveness rate.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

24.

[Cefixime therapy in sinusitis].

Author: JordeW, SchataM

Sinusitis improvement
Gastrointestinal side effects

Cefixime was effective in treating 40 patients with sinusitis. All patients experienced cure or improvement in symptoms, with 10 reporting mild to moderate gastrointestinal side effects.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

26.

Cefixime in urinary tract infections with special reference to pediatrics: overview.

Author: FanosV, CataldiL

UTIs treatment
Side effects

Cefixime, a third-generation oral cephalosporin, has been shown to be effective in treating non-complicated urinary tract infections in both adults and children. Cefixime has a low rate of side effects and can be used as monotherapy or switch therapy in children.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

27.

Clinical role of Cefixime in community-acquired infections.

Author: DreshajSh, Doda-EjupiT, TolajI Q, MustafaA, KabashiS, ShalaN, GecaNj, AliuA, DakaA, BashaN

Cefixime efficacy

Cefixime was effective in treating community-acquired infections such as acute otitis media, lower respiratory tract infections, and uncomplicated urinary tract infections in children. It was well tolerated with minimal side effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

28.

[Clinical evaluation of cefixime in the treatment of acute uncomplicated cystitis].

Author: TogashiM, KubotaM, NagamoriS, AsanoY, ImanakaK, GotohT, NonomuraK, KoyanagiT, ArakawaM, KakizakiH

Cystitis treatment
Excellent efficacy
Satisfactory treatment
Heaviness in the head

Cefixime was effective in treating acute uncomplicated cystitis, with an 80.8% excellent clinical efficacy rate and a low incidence of side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Language : Japanese

29.

Noncomparative, open label, multicenter trial of cefixime for treatment of bacterial pharyngitis, cystitis and pneumonia in pediatric patients.

Author: RisserW L, BaroneJ S, ClarkP A, SimpkinsD L

Safe and effective treatment
Diarrhea
Mild side effects

Cefixime (8 mg/kg once daily) was found to be safe and effective in treating 206 children with pharyngitis, cystitis, or pneumonia. The most common side effect was diarrhea.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

30.

[Clinical study on cefixime granules in the field of pediatrics].

Author: HarutaT, KurokiS, KobayashiY

Safe for children
Tonsillitis treatment
UTI treatment
Elevated platelet counts

Cefixime (CFIX) granules were effective in treating tonsillitis and urinary tract infection in pediatric patients. The clinical effectiveness rate was 94.4% with no side effects observed.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

31.

[Clinical experiences with cefixime in the treatment of bacterial infections of the lower respiratory tract].

Author: KerstenW, MüskenH

Respiratory infection improvement
Diarrhea
Epigastric pain

Cefixime was effective in treating lower respiratory tract infections in 21 patients, with an overall efficacy rate of 94.4%. It was well-tolerated, with only two patients experiencing mild side effects.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : German

32.

[Efficacy and tolerability of cefixime in the treatment of otorhinolaryngeal infections in adults].

Author: PeynègreR, BossardB, GehannoP

Cefixime effectiveness
ENT infection treatment
Minor abdominal discomfort

Cefixime was effective and well-tolerated in treating ENT infections in adults, including sinusitis, otitis media, and other infections.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Language : French

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