Paper Details

  1. Home
  2. Paper Details

Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review.

Author: AndridgeRebecca, HellingsJessica A, JainSeema

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This chart review assessed the effectiveness of loxapine substitution in patients with autism spectrum disorder (ASD) who developed antipsychotic-induced metabolic illness. The study found that low dose loxapine addition enabled taper of offending antipsychotics, significantly reversed drug-induced metabolic disturbances and improved irritability.
Paper Details　
Original Abstract of the Article :
Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received l...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s10803-015-2675-3

データ提供：米国国立医学図書館（NLM）

Loxapine: A Potential Solution for Antipsychotic-Induced Metabolic Disturbances

The use of antipsychotic medications can sometimes lead to undesirable side effects, such as weight gain and metabolic disturbances. This study explores the potential of loxapine, an atypical antipsychotic, to help manage these metabolic complications. The authors conducted a chart review of 15 adolescents and adults with autism spectrum disorder who experienced weight gain and other metabolic problems as a result of antipsychotic medication. They found that adding loxapine to their treatment regimen led to significant weight loss, reductions in body mass index, and improvements in triglyceride levels. This suggests that loxapine may be a helpful tool for managing the metabolic side effects of antipsychotic medications.

Loxapine: A Potential Solution for Metabolic Disturbances

The study's results, like a welcome respite in the desert, offer a potential solution for patients experiencing metabolic disturbances related to antipsychotic medications. Loxapine, when used in conjunction with other treatments, demonstrated significant improvements in weight, body mass index, and triglyceride levels. These results suggest that loxapine may be a valuable tool for managing the metabolic side effects of antipsychotics, offering relief for patients struggling with these complications.

Managing Metabolic Side Effects of Antipsychotics

This study provides valuable insights into the potential use of loxapine for managing metabolic side effects associated with antipsychotic medications. It's crucial to consult with a healthcare professional for personalized guidance and to discuss the potential benefits and risks of adding loxapine to a treatment regimen.

Dr.Camel's Conclusion

This study highlights the potential of loxapine as a valuable tool for managing metabolic disturbances associated with antipsychotic medications. It offers a glimmer of hope for patients who are struggling with these side effects, and it underscores the importance of continued research to find effective solutions for managing the metabolic complications of antipsychotic treatment.

Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26687568

DOI: Digital Object Identifier

10.1007/s10803-015-2675-3

Related Literature

Article Analysis
・Side Effects of loxapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.