Therapeutic and side-effect profile of a selective and reversible MAO-A inhibitor, brofaromine. Results of dose-finding trials in depressed patients.

Author: Delini-StulaA, HeathW R, SchiwyW

Paper Details 
Original Abstract of the Article :
Brofaromine (CGP 11 305 A), a new reversible and selective MAO-A inhibitor, was studied in two multicentre, (Trial A and Trial B) double-blind, dose-finding trials in a total of 124 depressed in-patients. Doses of 25, 50 and 75 mg bid were compared, to determine which was the most effective. The dur...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2677240

データ提供:米国国立医学図書館(NLM)

Brofaromine: A New Approach to Treating Depression

This study delves into the intricate world of depression, exploring the potential of a new medication, brofaromine, as a treatment option. It's like a camel caravan venturing into a vast and often misunderstood desert, seeking a path to relief from the debilitating effects of depression.

The study highlights the limitations of existing antidepressant treatments, particularly the challenges of side effects and effectiveness. It's like a desert traveler encountering treacherous sandstorms and mirages, with uncertainty lingering over the path to recovery. The study focuses on brofaromine, a novel and selective MAO-A inhibitor, as a potential alternative with improved efficacy and tolerability.

A New Path to Recovery: Brofaromine's Potential

The study reveals that brofaromine showed promising results in treating depression, particularly in individuals with "endogenous" depression. It's like a camel caravan finding a sturdy bridge across a treacherous river, allowing for safer passage. The study highlights the effectiveness of brofaromine in reducing depression symptoms, demonstrating its potential as a valuable treatment option.

Navigating the Desert of Depression: A Journey Toward Well-being

This research emphasizes the importance of exploring new treatment options for depression, a condition that affects millions worldwide. It's like a desert oasis, offering hope and relief to those struggling with the challenges of depression. This research encourages continued investigation into the potential of brofaromine and other novel therapies, potentially leading to more effective and personalized treatment approaches.

Dr.Camel's Conclusion

This study provides valuable insights into the potential of brofaromine as a novel treatment option for depression. It's like a compass guiding us through the desert of mental health, offering hope and direction for individuals seeking relief from the debilitating effects of depression. This research emphasizes the importance of ongoing research and development in the field of mental health, paving the way for more effective and compassionate care.

Date :
  1. Date Completed 1989-11-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2677240

DOI: Digital Object Identifier

2677240

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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