Paper Details

  1. Home
  2. Paper Details

Risk of Late Relapse or Reinfection With Hepatitis C Virus After Achieving a Sustained Virological Response: A Systematic Review and Meta-analysis.

Author: CookeGraham S, HillAndrew, RileyRichard D, SaleemJawaad, SimmonsBryony

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

SVR appears durable in the majority of patients at 5 years post-treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Treatment for hepatitis C virus (HCV) can lead to sustained virological response (SVR) in over 90% of people. Subsequent recurrence of HCV, either from late relapse or reinfection, reverses the beneficial effects of SVR. METHODS: A search identified studies analysing HCV recurrence post...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772843/

データ提供：米国国立医学図書館（NLM）

Hepatitis C: A Persistent Desert Storm

The fight against hepatitis C virus (HCV) is like a battle against a relentless desert storm. This research delves into the potential for late relapse or reinfection with HCV after achieving sustained virological response (SVR). The authors conducted a systematic review and meta-analysis to assess the risk of HCV recurrence. Their findings suggest that while SVR is durable in most patients, there is a significant risk of reinfection, particularly in high-risk groups, such as injecting drug users and prisoners. This research underscores the importance of ongoing monitoring and prevention strategies to combat this persistent threat.

Reinfection Risk: A Sandstorm in the Desert of Recovery

The study reveals a sobering truth: the risk of reinfection remains a significant challenge in the fight against HCV. Like a persistent sandstorm, reinfection can hinder the progress made during treatment. The findings highlight the need for comprehensive prevention programs to reduce the risk of reinfection, especially in high-risk populations.

Staying Vigilant in the Desert of Hepatitis C

Hepatitis C, like a desert mirage, can be deceptive. While treatment can lead to SVR, the risk of reinfection remains a constant threat. It's essential to stay informed and practice safe behaviors to minimize the risk of exposure to this virus. Just as a camel adapts to the harsh desert environment, we must be vigilant in our efforts to protect ourselves from this tenacious foe.

Dr.Camel's Conclusion

This study reminds us that even in the face of significant advancements in medicine, the battle against HCV is far from over. We must continue to invest in research, develop effective prevention strategies, and provide comprehensive care for those at risk of reinfection. Just as a camel relies on its strength and resilience to navigate the desert, we must remain steadfast in our efforts to combat this formidable challenge.

Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

26787172

DOI: Digital Object Identifier

PMC4772843

Related Literature

Article Analysis
・Effective treatment of hepatitis c
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.