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Pharmacodynamics of transdermal granisetron in women with nausea and vomiting of pregnancy.

Author: CaritisSteve, ChenHui-Jun, VenkataramananRaman, ZhaoYang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Granisetron significantly improved symptoms of nausea and vomiting as gauged by the PUQE score. After IV infusion the reduction in PUQE score was observed within 1 day. When granisetron was administered as a patch, benefit likewise was seen within 1 day. The beneficial effect of transdermal granisetron on the PUQE score persisted for the entire 7 days during which the patch was in place.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Limited options exist for women with nausea and vomiting of pregnancy (NVP) who cannot tolerate oral intake. Transdermal delivery of granisetron, a 5-hydroxytryptamine-3 receptor antagonist, provides an effective alternative for such patients. OBJECTIVE: The objective of this study was ...See full text at original site
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引用元：
https://doi.org/10.1016/j.ajog.2016.01.163

データ提供：米国国立医学図書館（NLM）

Transdermal Granisetron for Nausea and Vomiting: A Camel's Journey Through the Desert of Pregnancy

Nausea and vomiting during pregnancy, much like a sandstorm in the desert, can be a formidable challenge. This research explores the use of transdermal granisetron in women experiencing nausea and vomiting, offering a new oasis of hope for those seeking relief from this debilitating condition. The study examines the effectiveness of transdermal granisetron in alleviating symptoms, highlighting its potential as a safe and effective alternative for women who cannot tolerate oral medications. It's like a camel seeking a new source of water in a parched desert, exploring alternative options to quench its thirst.

Transdermal Granisetron: A New Oasis in the Desert of Pregnancy

This research shines a light on the potential benefits of transdermal granisetron in treating nausea and vomiting during pregnancy, offering a possible solution to alleviate this distressing condition. It's like discovering a new oasis in the desert, providing hope and relief for those struggling with pregnancy-related nausea and vomiting. The study's findings suggest that transdermal granisetron could be a valuable tool in managing these symptoms, promoting a more comfortable and enjoyable pregnancy journey.

Navigating the Desert of Pregnancy: Transdermal Granisetron as a Guide

This research provides a valuable guide for navigating the challenging terrain of pregnancy, offering hope for those struggling with nausea and vomiting. It's like a camel's intuition leading it to a hidden oasis, providing a potential solution for managing this debilitating condition. The study's findings pave the way for future advancements in pregnancy care.

Dr.Camel's Conclusion

This research highlights the potential benefits of transdermal granisetron in treating nausea and vomiting during pregnancy, offering a new oasis of hope for those seeking relief from this distressing condition. It's like finding a hidden oasis in the desert, providing a potential solution for improving overall pregnancy outcomes.

Date :
  1. Date Completed 2017-05-16
  2. Date Revised 2018-01-10
Further Info :

Pubmed ID

26812081

DOI: Digital Object Identifier

10.1016/j.ajog.2016.01.163

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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