An upcoming drug for onychomycosis: Tavaborole.

Author: SharmaDhruva, SharmaNeha

Paper Details 
Original Abstract of the Article :
Fungal infection of the nail as well as nail bed is termed as 'onychomycosis'. It is caused by dermatophytes, non-dermatophytic fungal species and yeasts like Candida albicans. It is traditionally treated by topical antifungals, systemic agents like ketoconazole, griseofulvin, itraconazole, fluconaz...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714399/

データ提供:米国国立医学図書館(NLM)

A New Hope for Nail Fungus: Tavaborole

The world of dermatology is always on the lookout for new and effective treatments, and fungal infections are no exception. Onychomycosis, a fungal infection of the nail and nail bed, can be a real pain (pun intended!). It's often treated with topical antifungals and systemic agents, but finding a drug with few side effects and good patient compliance has always been a challenge. Enter Tavaborole, the first oxaborole antifungal agent approved by the FDA in 2014. This innovative treatment, marketed under the trade name 'Kerydin,' works by inhibiting protein synthesis in the fungus. It's like a little camel in the desert who sits down right on the protein production path, effectively blocking the fungus from growing. While there are some reported side effects like dermatitis, the overall picture is positive. This research dives into the chemical nature, mechanism of action, and clinical trial findings of Tavaborole, offering hope for podiatrists and patients alike.

Tavaborole: A Promising Solution for Nail Fungus

The results of two completed phase 3 clinical trials showed promising outcomes for Tavaborole in treating onychomycosis. This could be a game-changer for patients suffering from this stubborn fungal infection, offering a new avenue for treatment with fewer side effects.

The Future of Treating Nail Fungus

While Tavaborole offers a promising solution, it's important to remember that it's not a cure-all. Like a thirsty traveler in the desert, a patient might need to stay hydrated with regular treatment to see the best results. This research underscores the importance of continued research and development in the field of dermatology, especially in finding effective treatments with minimal side effects.

Dr.Camel's Conclusion

This research sheds light on a promising new treatment for onychomycosis, paving the way for better options for patients. Tavaborole's innovative approach could be a real game-changer in the field of dermatology, providing a solution that's more effective and less bothersome for those seeking relief from this fungal infection. It's a reminder that even in the vast desert of medical challenges, there are always new oases of hope waiting to be discovered.

Date :
  1. Date Completed 2016-01-28
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

26816482

DOI: Digital Object Identifier

PMC4714399

Related Literature

SNS
PICO Info
in preparation
Languages

English

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