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Spontaneous motor activity in healthy volunteers after single doses of haloperidol.

Author: BenteG, FreyS, FuchsA, GlattA, ImhofP, PreiswerkG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Haloperidol induced characteristic changes in motor activity, including a reduction in extremity motility and prolongation of movement and immobility phases of the head.
Paper Details　
Original Abstract of the Article :
Video recordings of the spontaneous motor activity of 6 healthy volunteers after treatment with 0.75 mg haloperidol i.v., or placebo, were transcribed into a time-series protocol of motor behaviour. Characteristic changes seen after the injection of haloperidol consisted in a reduction of the motili...See full text at original site
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引用元：
https://doi.org/10.1097/00004850-198901000-00005

データ提供：米国国立医学図書館（NLM）

The Effects of Haloperidol on Spontaneous Motor Activity

Haloperidol, an antipsychotic medication, is known to have effects on motor function. This research investigates the impact of a single dose of haloperidol on spontaneous motor activity in healthy volunteers. The study employed video recordings to analyze changes in motor behavior after administering haloperidol or placebo. The researchers observed distinct changes in motor activity, including reduced extremity motility and altered head movement patterns, after haloperidol administration. These findings provide valuable insights into the neuropharmacological effects of haloperidol on motor function.

Unraveling the Mysteries of Motor Control

This study offers a glimpse into the complex interplay between medication and motor control. By examining the changes in motor activity after haloperidol administration, the researchers provide evidence for the drug's impact on various aspects of movement. This knowledge is essential for understanding the mechanisms of action of antipsychotics and their potential side effects. Imagine this like observing a desert animal's movement – understanding the changes in its behavior after a specific intervention reveals valuable insights into its physiology.

Navigating the Side Effects of Antipsychotics

This research underscores the importance of considering the potential side effects of antipsychotics, specifically those affecting motor function. The observed changes in motor activity after haloperidol administration highlight the need for careful monitoring and management of these side effects in patients. It's like navigating a desert with shifting sand – understanding the potential hazards and taking necessary precautions is crucial for a safe and successful journey.

Dr. Camel's Conclusion

This research provides valuable insights into the effects of haloperidol on spontaneous motor activity. The researchers' observations highlight the drug's influence on different aspects of movement, emphasizing the need for careful monitoring and management of potential side effects in patients. This research, like discovering a hidden spring in the desert, reminds us of the intricate connections between medications and motor function.
Date :
  1. Date Completed 1990-01-12
  2. Date Revised 2019-10-22
Further Info :

Pubmed ID

2687356

DOI: Digital Object Identifier

10.1097/00004850-198901000-00005

SNS
PICO Info
in preparation
Languages

English

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