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The Cancer Research Campaign trials of adjuvant therapy for early breast cancer.

Author: A'HernR P, BaumM, EbbsS R, HoughtonJ, RileyD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Systemic treatment is needed to cure early breast cancer, as tumor spread is common. The Cancer Research Campaign Breast Adjuvant Trial found that both perioperative cyclophosphamide and long-term tamoxifen improved outcomes.
Paper Details　
Original Abstract of the Article :
It is now assumed that for many women there has already been dissemination of tumour at the time of diagnosis of their early breast cancer. Systemic treatment is required if a cure is sought. The use of perioperative cyclophosphamide and long-term tamoxifen, either as single agents or in combination...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.3109/02841868909092330

データ提供：米国国立医学図書館（NLM）

Adjuvant Therapy for Early Breast Cancer: A Crucial Step

Early detection is crucial in the fight against breast cancer, but even early-stage tumors can spread to other parts of the body. This study explores the use of adjuvant therapy, given after surgery, to improve outcomes for women diagnosed with early breast cancer. Researchers conducted the Cancer Research Campaign Breast Adjuvant Trial, evaluating the effectiveness of perioperative cyclophosphamide and long-term tamoxifen, both as single agents and in combination, in treating early breast cancer.

The Benefits of Adjuvant Therapy

The study's findings, involving over 2,200 women, revealed a significant benefit from both cyclophosphamide and tamoxifen. This data suggests that adjuvant therapy can play a crucial role in improving the chances of long-term survival for women with early breast cancer. It's like adding a vital layer of defense, akin to a protective wall surrounding a desert oasis, against the potential spread of cancer.

Improving Outcomes for Women with Early Breast Cancer

This study, like a compass guiding a traveler through a vast desert, provides valuable insights into the importance of adjuvant therapy in the treatment of early breast cancer. The findings suggest that these therapies can significantly improve outcomes for women diagnosed with this disease. It's like discovering a hidden source of water in the desert, providing a vital resource for fighting the disease and improving the chances of survival.

Dr. Camel's Conclusion

This study, like a desert caravan seeking a safe passage through treacherous terrain, investigates the effectiveness of adjuvant therapy in the treatment of early breast cancer. The findings highlight the critical role of these therapies in improving outcomes for women diagnosed with this disease. It's like discovering a hidden oasis in the desert of cancer treatment, offering a crucial resource for fighting the disease and improving the chances of survival.

Date :
  1. Date Completed 1990-03-08
  2. Date Revised 2019-09-03
Further Info :

Pubmed ID

2692654

DOI: Digital Object Identifier

10.3109/02841868909092330

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Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

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