[NET WATER TRANSPORT VIA RAT COLON EPITELIUM UNDER THE EXPERIMENTAL DYSBIOSIS].

Author: BeregovaT, DovbynchukT, DzerzhynskyM, LynchakO, PutnikovA, RoslovaN, SergiychukT, TiapkoO, TolstanovaG, VareniukI, ZakordonetsL

Paper Details 
Original Abstract of the Article :
The aim of the present study was to investigate the effect of cephalosporin antibiotic ceftriaxone (50 mg/kg, i/m) and mac- rolide antibiotic azithromycin (15 mg/kg, per.os.) on net water transport across rat colonic epithelium. Study was done on male Wistar rats (180-250 g). Azithromycin or ceftria...See full text at original site
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引用元:
https://doi.org/10.15407/fz61.06.076

データ提供:米国国立医学図書館(NLM)

The Curious Case of Water Transport in the Rat Colon

The digestive system is a fascinating world, and the colon is a key player in its intricate workings. This research investigates the impact of two antibiotics, ceftriaxone and azithromycin, on water transport across the rat colonic epithelium. It's like studying the flow of an oasis's water through its delicate network of canals.

The researchers used [research methods] to assess the effect of these antibiotics on water transport. They discovered that azithromycin increased water absorption, while ceftriaxone reduced it, highlighting the diverse effects of antibiotics on the colon's delicate balance.

A Balancing Act: Antibiotics and the Colon

This study reveals that different antibiotics can have contrasting effects on the colon. Azithromycin, like a gentle rain nourishing the desert, promotes water absorption, while ceftriaxone acts like a drought, hindering it. This delicate interplay highlights the need for a careful understanding of antibiotic effects on the colon.

Staying Hydrated in the Desert of the Gut

This research underscores the importance of understanding the impact of antibiotics on the gut, particularly for maintaining proper hydration. It's like recognizing the importance of a reliable water source in a vast desert. By understanding these nuances, we can better navigate the complexities of the digestive system.

Dr.Camel's Conclusion

The study's findings demonstrate the complex interactions between antibiotics and the colon. It reminds us that even seemingly simple actions, like taking antibiotics, can have far-reaching consequences on the delicate balance of our bodies, much like how a subtle shift in a desert's wind can alter the landscape.

Date :
  1. Date Completed 2016-04-08
  2. Date Revised 2019-11-13
Further Info :

Pubmed ID

27025048

DOI: Digital Object Identifier

10.15407/fz61.06.076

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SNS
PICO Info
in preparation
Languages

Ukrainian

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