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Evaluation of the abuse potential of methocarbamol.
Author: GriffithsR R, GuarinoJ J, KirkW T, PrestonK L
Original Abstract of the Article :
The subjective and behavioral effects of p.o. administered methocarbamol, lorazepam and placebo were studied in a nonresidential group of adult male volunteers with histories of recreational substance abuse including sedative/hypnotics. In the first phase of the investigation, a dose run-up of metho...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2703967
データ提供:米国国立医学図書館(NLM)
Methocarbamol: Exploring the Oasis of Potential Abuse
Methocarbamol is a muscle relaxant commonly used to treat muscle spasms and pain, but like a hidden oasis in the desert, it also has a potential for abuse. This study explores the abuse potential of methocarbamol, comparing its effects to those of lorazepam, a known sedative-hypnotic.
The authors conducted a study involving volunteers with histories of substance abuse, administering methocarbamol and lorazepam at various doses. They assessed the subjective and behavioral effects of these drugs, including measures of drug liking, psychomotor performance, and cognitive function. The results indicated that methocarbamol, at high doses, produced some subjective effects similar to those of lorazepam, suggesting a potential for abuse. However, the authors noted that methocarbamol's potential for abuse was likely lower than that of lorazepam due to the accompanying side effects at high doses.
A Reminder of the Desert's Hidden Dangers
This study serves as a reminder that even seemingly harmless medications can have a potential for abuse. It's like discovering a hidden oasis in the desert, beautiful and alluring, but also potentially dangerous if not approached with caution.
Navigating the Desert of Medication Abuse
This research highlights the importance of careful monitoring and responsible use of medications, even those that are generally considered safe. It's a reminder that the desert of medication abuse can be deceptively dangerous, requiring us to be vigilant and informed.
Dr.Camel's Conclusion
This study encourages us to be mindful of the potential for abuse, even with medications that are generally considered safe. It's a reminder that the desert of medicine can hold both healing and hidden dangers, and navigating it requires caution and awareness.
Date :
- Date Completed 1989-05-12
- Date Revised 2015-11-19
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English
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