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Fibroid interventions: reducing symptoms today and tomorrow: extending generalizability by using a comprehensive cohort design with a randomized controlled trial.

Author: AbdElmagiedAhmed M, BorahBijan J, GornyKrzysztof R, HesleyGina K, JacobyVanessa L, KohiMaureen P, Laughlin-TommasoShannon K, LemensMaureen A, LeppertPhyllis C, MillerMichael J, NievesAngel, PriceThomas M, StewartElizabeth A, VaughanLisa E, WeaverAmy L, WoodrumDavid A

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Uterine fibroids are a common problem for women of reproductive age, and hysterectomy is the most common treatment despite many alternatives. This study aims to compare two minimally invasive treatments for fibroids – uterine artery embolization and magnetic resonance imaging-guided focused ultrasound surgery – to hysterectomy. While randomized trials are the gold standard for comparing treatments, they are difficult to conduct for fibroid treatments. This study will also collect data on women who choose not to participate in the randomized trial to provide further information on the effectiveness of these treatments.
Paper Details　
Original Abstract of the Article :
Uterine fibroids are an important source of morbidity for reproductive-aged women. Despite an increasing number of alternatives, hysterectomies account for about 75% of all fibroid interventional treatments. Evidence is lacking to help women and their health care providers decide among alternatives ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/27073063

データ提供：米国国立医学図書館（NLM）

Fibroid Interventions: Navigating the Desert of Treatment Options

This study examines the effectiveness of minimally invasive interventions for uterine fibroids, a common condition affecting women of reproductive age. The authors highlight the need for robust evidence to guide treatment decisions, as hysterectomy remains the most common intervention despite the increasing availability of alternative treatments. The Fibroid Interventions: Reducing Symptoms Today and Tomorrow (FIRST) trial is a randomized controlled trial comparing the safety, efficacy, and economics of two minimally invasive alternatives to hysterectomy: uterine artery embolization and magnetic resonance imaging-guided focused ultrasound surgery. This research contributes to the growing body of evidence on minimally invasive treatments for uterine fibroids, empowering women and their healthcare providers to make informed decisions about their care.

Finding the Right Oasis in the Desert of Fibroid Treatment Options: A Comprehensive Approach to Comparative Effectiveness Research

Imagine the desert of uterine fibroids, a challenging landscape for women seeking effective treatment. This research delves into the effectiveness of minimally invasive interventions for fibroids, providing valuable insights to guide treatment decisions. The authors recognize the need for strong evidence to compare the safety, efficacy, and economics of different treatment options, helping women and their healthcare providers navigate the complexities of fibroid management. This research underscores the importance of robust comparative effectiveness research in guiding clinical practice and empowering patients to make informed choices about their care.

A Desert Oasis of Choice: Empowering Women with Informed Decisions

This research underscores the importance of patient choice and informed decision-making in healthcare. By providing comprehensive evidence on different treatment options for uterine fibroids, this study empowers women to actively participate in their care and make informed decisions aligned with their values and priorities.

Dr. Camel's Conclusion

This research is a testament to the dedication of scientists in improving women’s health. By providing robust evidence on minimally invasive interventions for uterine fibroids, this study paves the way for personalized treatment plans that empower women to make informed decisions about their care.

Date :
  1. Date Completed 2017-05-25
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27073063

DOI: Digital Object Identifier

NIHMS791180

Related Literature

Article Analysis
・Effective treatment of uterine fibroids
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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