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Chlorpromazine versus reserpine for schizophrenia.

Author: AdamsClive E, NurSelin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Reserpine, an antipsychotic drug, was widely used in the 1940s but has since been withdrawn due to its irreversible pharmacological potency and adverse effects. Chlorpromazine, another older antipsychotic, remains in use for treating schizophrenia.
Paper Details　
Original Abstract of the Article :
In the 1940s reserpine, refined from a plant extract that had been used for centuries, began to be used as a treatment for people with mental disorders and was one of the very first antipsychotic drugs. Its irreversible pharmacological potency and adverse effects meant that it has been withdrawn in ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350329/

データ提供：米国国立医学図書館（NLM）

Chlorpromazine and Reserpine: A Historical Perspective on Schizophrenia Treatment

The history of medicine is filled with fascinating stories of discovery and innovation. This study delves into the early days of antipsychotic treatment for schizophrenia, focusing on two pioneering medications: chlorpromazine and reserpine. The researchers provide a historical perspective on these drugs, highlighting their impact on the field of psychiatry and the evolution of treatment approaches.

From the Past to the Present: A Journey Through Schizophrenia Treatment

The study traces the development and use of reserpine and chlorpromazine, highlighting their significance as early antipsychotics. While reserpine has largely been superseded by newer medications due to its adverse effects, chlorpromazine remains a relevant treatment option for schizophrenia. This historical perspective offers valuable insights into the evolution of our understanding of schizophrenia and the ongoing quest for effective treatments.

Understanding the Past, Shaping the Future: A Legacy of Innovation

This study serves as a reminder of the remarkable progress made in the field of mental health treatment. By examining the history of reserpine and chlorpromazine, we gain a deeper appreciation for the evolution of our understanding of schizophrenia and the ongoing search for better treatments. This historical perspective informs our approach to current and future research, guiding our efforts to improve the lives of those living with schizophrenia.

Dr.Camel's Conclusion

This study is like a camel caravan journeying through time, revealing the historical evolution of schizophrenia treatment. By exploring the past, we gain a deeper understanding of the present and future of mental health care, forging a path towards better outcomes for patients.

Date :
  1. Date Completed 2016-07-21
  2. Date Revised 2023-07-18
Further Info :

Pubmed ID

27124109

DOI: Digital Object Identifier

PMC10350329

Related Literature

Article Analysis
・Effects of reserpine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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