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The Effect of Garlic Derivatives (S-Allylmercaptocysteine, Diallyl Disulfide, and S-Allylcysteine) on Gentamicin Induced Ototoxicity: An Experimental Study.
Author: AcarGul Ozbilen, CamOsman Halit, KalciogluM Tayyar, KoktenNuman, TekinMuhammet, UgurM Birol, UzunLokman
Original Abstract of the Article :
Gentamicin is a potent aminoglycoside antibiotic. Ototoxicity and nephrotoxicity are the main side effects which restrict the use of gentamicin. Garlic with its intrinsic antioxidant activity may prove beneficial in prevention from ototoxicity. S-allylmercaptocysteine (SAMC), diallyl disulfide (DD),...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115152/
データ提供:米国国立医学図書館(NLM)
Garlic: A Natural Weapon Against Ototoxicity
This research ventures into the world of antibiotic therapies and their potential side effects, specifically focusing on gentamicin, a powerful antibiotic known for its effectiveness against bacterial infections but also its potential to cause ototoxicity, damage to the ears. Imagine a desert where the oasis of healing is sometimes accompanied by unintended consequences. The study investigates the protective effects of garlic derivatives, SAMC, DD, and SAC, against gentamicin-induced ototoxicity in rats. Garlic, with its rich antioxidant properties, has been shown to have potential benefits for preventing various health issues.
Garlic's Antioxidant Shield: A Defense Against Ototoxicity
The study found that these garlic derivatives, when administered to rats, provided protection against gentamicin-induced ototoxicity, as measured by brainstem evoked response audiometry. This suggests that garlic might offer a natural way to mitigate the potential side effects of gentamicin, helping to preserve hearing health.
A Culinary Ally in the Desert of Health
This research highlights the potential of garlic as a natural ally in the desert of health, offering protection against the adverse effects of certain medications. This study suggests that incorporating garlic into our diets might contribute to overall well-being.
Dr.Camel's Conclusion
This study is like discovering a hidden oasis in the desert of antibiotic therapy, highlighting the potential of garlic derivatives to protect against gentamicin-induced ototoxicity. This research adds to the growing body of evidence supporting the benefits of garlic for overall health.
Date :
- Date Completed n.d.
- Date Revised 2020-09-30
Further Info :
Related Literature
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