Five-Year Outcomes with Anti-Vascular Endothelial Growth Factor Treatment of Neovascular Age-Related Macular Degeneration: The Comparison of Age-Related Macular Degeneration Treatments Trials.

Author: , DanielEbenezer, FerrisFrederick L, FineStuart L, GrunwaldJuan E, JaffeGlenn J, MaguireMaureen G, MartinDaniel F, TothCynthia A, YingGui-Shuang

Paper Details 
Original Abstract of the Article :
PURPOSE: To describe outcomes 5 years after initiating treatment with bevacizumab or ranibizumab for neovascular age-related macular degeneration (AMD). DESIGN: Cohort study. PARTICIPANTS: Patients enrolled in the Comparison of AMD Treatments Trials. METHODS: Patients were assigned randomly to ra...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/27156698

データ提供:米国国立医学図書館(NLM)

Long-Term Vision: Anti-VEGF Treatment for Age-Related Macular Degeneration

Imagine a vast desert landscape, where a shimmering oasis represents a potential solution for a challenging problem. This is similar to the search for effective treatments for age-related macular degeneration (AMD), a leading cause of vision loss. This study examines the long-term outcomes of anti-vascular endothelial growth factor (VEGF) therapy for neovascular AMD, focusing on the 5-year results of two major clinical trials.

Anti-VEGF Therapy: Sustaining Vision Gains

The study found that anti-VEGF therapy, using either bevacizumab or ranibizumab, resulted in significant vision gains during the first 2 years of treatment. While these gains were not fully maintained at the 5-year mark, a substantial proportion of patients still had good vision. This suggests that anti-VEGF therapy can provide sustained vision benefits for a significant number of patients with neovascular AMD. The study also found that there were no significant differences in outcomes between the two drugs or the different dosing regimens.

A Beacon of Hope for Vision Preservation

This research provides valuable insights into the long-term effectiveness of anti-VEGF therapy for neovascular AMD. This study is like a compass guiding us through the desert of AMD research, helping to understand the long-term impact of this therapy and refine treatment strategies to maximize vision preservation. It offers a glimmer of hope for individuals facing the challenges of AMD.

Dr.Camel's Conclusion

Anti-VEGF therapy, like a refreshing oasis in the desert of vision loss, has revolutionized the treatment of neovascular AMD. This study reminds us that the journey to preserving vision is ongoing, and continued research is essential for finding new and improved treatments. This research is like a sandcastle built with care, offering a structure of knowledge and hope for those affected by AMD.

Date :
  1. Date Completed 2017-06-30
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

27156698

DOI: Digital Object Identifier

NIHMS776214

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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