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Henoch-Schönlein purpura and drug and vaccine use in childhood: a case-control study.

Author: , BarabinoPaola, CompagnoneAdele, Da CasRoberto, Da DaltLiviana, Di PietroPasquale, Menniti-IppolitoFrancesca, MoresNadia, RaucciUmberto, RennaSalvatore, RiceputiLaura, ScanferlaStefania, StrafellaMaria Stefania, ZerbinatiClaudia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study aimed to estimate the association of Henoch-Schönlein purpura (HSP), a common childhood vasculitis, with drug and vaccine administration in a pediatric population. While the etiology of HSP is unknown, infectious agents, drugs, and vaccines have been proposed as triggers.
Paper Details　
Original Abstract of the Article :
Henoch-Schönlein purpura (HSP) is the most common vasculitis in childhood; nevertheless, its etiology and pathogenesis remain unknown despite the fact that a variety of factors, mainly infectious agents, drugs and vaccines have been suggested as triggers for the disease. The aim of this study was to...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912703/

データ提供：米国国立医学図書館（NLM）

Henoch-Schönlein Purpura: Exploring Potential Triggers

Henoch-Schönlein purpura (HSP) is a common vasculitis in children, but its underlying causes are not fully understood. This case-control study aimed to investigate the potential association of HSP with drug and vaccine administration. The researchers compared a group of children with HSP to a control group without HSP, analyzing the exposure to various drugs and vaccines in both groups. The study found no significant association between HSP and drug or vaccine administration.

Henoch-Schönlein Purpura: A Complex Puzzle

While this study did not find a significant association between HSP and drug or vaccine administration, it does not rule out the possibility of rare cases triggered by specific medications or vaccines. Further research is needed to explore the potential role of other environmental factors, such as infections, in the development of HSP.

Navigating the Desert of Vasculitis: Seeking Answers

Understanding the causes of HSP is essential for developing effective prevention and treatment strategies. This study provides valuable insights into the potential role of drugs and vaccines, but further exploration of other potential triggers is needed to unravel the complex puzzle of HSP.

Dr.Camel's Conclusion

The search for the causes of HSP is like a camel searching for a hidden oasis in the desert. While this study did not uncover a link to drug or vaccine administration, it highlights the ongoing quest to understand this complex condition and develop effective strategies for prevention and treatment.

Date :
  1. Date Completed 2017-07-19
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

27316345

DOI: Digital Object Identifier

PMC4912703

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Languages

English

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