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The effects of second generation antipsychotic drugs on sleep variables in healthy subjects and patients with schizophrenia.
Author: MontiJaime M, Pandi PerumalSeithikurippu R, TorteroloPablo
Original Abstract of the Article :
Insomnia is a common feature in schizophrenia, and is characterized by an increase of sleep latency (SL), as well as reductions in total sleep time (TST) and sleep efficiency (SE). Regarding sleep architecture, non-rapid-eye-movement (NREM) sleep, slow wave sleep (SWS) and rapid-eye-movement (REM) s...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://doi.org/10.1016/j.smrv.2016.05.002
データ提供：米国国立医学図書館（NLM）
Second Generation Antipsychotics and Sleep
The desert of mental illness can be a challenging landscape, and sleep disturbances are a common and debilitating symptom of schizophrenia. This study delves into the effects of second generation antipsychotic drugs on sleep variables in both healthy subjects and patients with schizophrenia. The authors conducted a comprehensive review of existing polysomnographic studies, examining the impact of various antipsychotic medications on sleep latency, total sleep time, sleep efficiency, and sleep architecture.
Second Generation Antipsychotics: Mixed Effects on Sleep
The study revealed that second generation antipsychotics, including clozapine, olanzapine, and paliperidone, often improved sleep in patients with schizophrenia, reducing sleep latency and increasing total sleep time and sleep efficiency. However, the study also found that quetiapine administration disrupted sleep, further emphasizing the need for careful consideration when selecting antipsychotic medications for patients with sleep disturbances.
Finding Balance in the Desert of Mental Illness
As a desert wanderer, I recognize the importance of a good night's rest to navigate the challenges of life. This study provides valuable insights into the complex relationship between antipsychotic medications and sleep in patients with schizophrenia. The findings highlight the need for personalized treatment strategies that address individual sleep needs and minimize the potential for sleep disruption.
Dr.Camel's Conclusion
This study provides a comprehensive overview of the effects of second generation antipsychotic drugs on sleep variables in both healthy subjects and patients with schizophrenia. The findings underscore the importance of considering individual sleep needs when prescribing these medications, particularly in patients with schizophrenia, where sleep disturbances are common and debilitating.
Date :
- Date Completed 2018-04-24
- Date Revised 2022-04-08
Further Info :
Related Literature
English
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