The onset risk of carcinoma in patients continuing tacrolimus topical treatment for oral lichen planus: a case report.

Author: AsodaSeiji, KawanaHiromasa, MoritaMayu, NakagawaTaneaki, NishikawaTakeji, ShirakawaMasayori, ShojiHirofumi, SomaTomoya, TsunodaKazuyuki, YagishitaHisao

Paper Details 
Original Abstract of the Article :
Oral lichen planus is a chronic inflammatory mucocutaneous disease. Topical use of steroids and other immuno-modulating therapies have been tried for this intractable condition. Nowadays, tacrolimus ointment is used more commonly as a choice for treatment. However, a number of discussions have taken...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352802/

データ提供:米国国立医学図書館(NLM)

Tacrolimus and Oral Lichen Planus: A Cautionary Tale in the Desert of Skin Health

Oral lichen planus is a chronic inflammatory mucocutaneous disease that can cause significant discomfort and affect quality of life. This case report describes a patient who developed squamous cell carcinoma after using tacrolimus ointment to treat oral lichen planus. The case highlights the potential carcinogenic effects of tacrolimus, a commonly used immunosuppressant. The researchers emphasize the need for careful consideration of the risks and benefits of using tacrolimus for oral lichen planus, particularly in light of its potential carcinogenic effects.

Navigating the Risks and Benefits of Tacrolimus

The case report serves as a reminder that even seemingly safe medications can have unintended consequences. Just as a camel must be wary of hidden dangers in the desert, healthcare providers and patients must carefully weigh the risks and benefits of using tacrolimus for oral lichen planus. The case highlights the importance of ongoing monitoring and careful consideration of alternative treatment options.

Protecting Your Skin: A Guide to Oral Lichen Planus

Individuals with oral lichen planus should work closely with their healthcare providers to develop a comprehensive treatment plan that minimizes risks and maximizes benefits. Just as a camel adapts to the harsh desert environment, patients must be proactive in managing their condition. Maintaining good oral hygiene, following a healthy diet, and seeking prompt medical attention for any unusual symptoms are essential aspects of managing oral lichen planus.

Dr.Camel's Conclusion

This case report serves as a stark reminder of the potential risks associated with certain medications. Like a wise camel navigating the treacherous landscape of the desert, healthcare professionals and patients must exercise caution and vigilance when using immunosuppressant medications. By carefully considering the risks and benefits and maintaining open communication, we can work together to protect our health and well-being.

Date :
  1. Date Completed 2018-03-12
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27368962

DOI: Digital Object Identifier

PMC5352802

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.