Paper Details

  1. Home
  2. Paper Details

Prophylactic treatment of postperfusion bleeding using EACA.

Author: BotrosS, CernaianuA C, DelRossiA J, LemoleG M, MooreR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Prophylactic treatment with EACA, a drug that reduces blood loss, decreased postoperative blood loss, myocardial infarctions, and cerebrovascular accidents in patients undergoing open-heart surgery. It also reduced the need for blood transfusions.
Paper Details　
Original Abstract of the Article :
To determine the effects of prophylactic treatment with EACA for blood loss after cardipulmonary bypass surgery, 350 consecutive patients undergoing open-heart surgery were studied. One hundred seventy patients received an initial dose of 5 g of EACA prior to skin incision, followed by intravenous a...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1378/chest.96.1.27

データ提供：米国国立医学図書館（NLM）

EACA: A Potential Solution for Postperfusion Bleeding

Open-heart surgery, while a marvel of modern medicine, can present challenges, particularly in managing postperfusion bleeding. This study investigates the effectiveness of prophylactic treatment with EACA (epsilon-aminocaproic acid) in reducing blood loss after cardiopulmonary bypass surgery. The authors compare a group of patients receiving EACA with a control group, analyzing various outcomes related to blood loss and complications.

EACA: A Promising Approach for Reducing Postperfusion Bleeding

This research, much like a skilled desert surgeon seeking to minimize blood loss during a delicate procedure, explores the potential of EACA to reduce postperfusion bleeding after open-heart surgery. The study finds that prophylactic EACA treatment significantly reduces chest tube blood loss and blood transfusion requirements, suggesting that it can be a valuable tool for managing this common complication. These findings highlight the potential of EACA to improve patient outcomes and minimize the risks associated with postperfusion bleeding.

Improving Outcomes in Open-Heart Surgery

This research, like a well-stocked oasis in the desert of open-heart surgery, offers valuable insights into managing postperfusion bleeding. By understanding the potential benefits of EACA, healthcare providers can make informed decisions about its use, potentially improving patient outcomes and minimizing complications. This research is a testament to the ongoing search for innovative solutions to improve the safety and effectiveness of open-heart surgery.

Dr.Camel's Conclusion

This research, much like a camel caravan carrying vital supplies across a treacherous desert, reveals the potential of EACA to effectively reduce postperfusion bleeding after open-heart surgery, enhancing patient safety and improving overall outcomes.
Date :
  1. Date Completed 1989-08-10
  2. Date Revised 2019-05-14
Further Info :

Pubmed ID

2736988

DOI: Digital Object Identifier

10.1378/chest.96.1.27

Related Literature

Article Analysis
・Side Effects of aminocaproic acid
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.