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Sublingual buprenorphine and pethidine for immediate postoperative pain relief in major gynecologic surgery: a comparative study.
Author: AeuwpadungS, ChandeyingV, SutthijumroonS, TungphaisalS
Original Abstract of the Article :
The analgesic effect of sublingual buprenorphine 0.4 mg has been compared with pethidine 1 mg/kg given intramuscularly in 80 patients following major gynecologic operation. The results indicate a slower onset of action for sublingual buprenorphine in the first two hours (p less than 0.001), but it h...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2738496
データ提供:米国国立医学図書館(NLM)
Exploring Pain Relief: A Comparative Study on Sublingual Buprenorphine and Pethidine
The realm of pain management is a vast desert, with researchers constantly searching for effective oases of relief. This study delves into the world of post-surgical pain, comparing the analgesic effects of two commonly used medications: sublingual buprenorphine and intramuscular pethidine. The study, conducted on 80 patients undergoing major gynecologic surgery, aimed to determine the effectiveness and duration of each medication's pain relief.
The researchers discovered that while sublingual buprenorphine had a slower onset of action in the first two hours, it ultimately provided a more prolonged and effective pain relief compared to pethidine. This difference in effectiveness was statistically significant, with p-values less than 0.001 for both onset time and overall pain relief. While both medications were associated with nausea and vomiting as potential side effects, the researchers found no significant difference in the occurrence of these side effects between the two treatment groups.
Sublingual Buprenorphine: A Longer-Lasting Oasis of Relief
The findings of this study suggest that sublingual buprenorphine may be a more effective option for post-surgical pain management than pethidine, offering a longer duration of pain relief. The researchers' findings highlight the importance of considering individual patient needs and the potential benefits of using sublingual buprenorphine, especially when prolonged pain relief is desired.
Navigating Post-Surgical Pain: Finding the Right Oasis
Patients undergoing major gynecologic surgery may experience varying degrees of pain, and it's crucial to find a pain relief strategy that works best for their individual needs. While sublingual buprenorphine offers a longer-lasting solution, it's essential to discuss potential side effects with your healthcare provider, including the possibility of nausea and vomiting.
Dr. Camel's Conclusion
This study reveals the importance of considering different pain relief options for post-surgical recovery. Like a camel traversing the vast desert, finding the right oasis of pain relief is essential for a smooth journey back to health. The researchers' findings suggest that sublingual buprenorphine, with its prolonged effectiveness, could be a valuable resource for patients seeking a more sustained respite from pain.
Date :
- Date Completed 1989-08-03
- Date Revised 2013-11-21
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English
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