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The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections.

Author: BlasiFrancesco, CazzolaMario, MateraMaria Gabriella, PageClive, PallecchiLucia, RoglianiPaola, RossoliniGian Maria

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

N-acetylcysteine (NAC) is a non-antibiotic treatment that may be effective in treating biofilm-related respiratory infections. NAC has been shown to reduce biofilm formation and increase the effectiveness of antibiotics. Further research is needed to determine the optimal dosage and duration of NAC treatment for these infections.
Paper Details　
Original Abstract of the Article :
In airway infections, biofilm formation has been demonstrated to be responsible for both acute and chronic events, and constitutes a genuine challenge in clinical practice. Difficulty in eradicating biofilms with systemic antibiotics has led clinicians to consider the possible role of non-antibiotic...See full text at original site
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引用元：
https://doi.org/10.1016/j.rmed.2016.06.015

データ提供：米国国立医学図書館（NLM）

Biofilms: A Sticky Problem for Respiratory Infections

The human respiratory system, a vast and intricate network of airways, is constantly under siege from bacteria and viruses. When these invaders form biofilms, a protective shield that makes them resistant to antibiotics, treatment becomes a formidable challenge. This review examines the potential of N-acetylcysteine (NAC), a non-antibiotic drug, as a weapon in the fight against biofilm-related respiratory infections.

Breaking the Biofilm Barrier: The Potential of NAC

NAC is a promising agent that has shown potential to disrupt biofilm formation and enhance the effectiveness of antibiotics. However, further research is needed to fully understand its role in treating these challenging infections.

Navigating the Respiratory Desert: The Search for Solutions

The battle against biofilm-related respiratory infections is an ongoing quest in the vast desert of medical research. Like explorers seeking a hidden oasis, scientists are constantly searching for new strategies to overcome these stubborn infections.

Dr.Camel's Conclusion

This review highlights the ongoing research into novel approaches for tackling biofilm-related respiratory infections. NAC is a promising candidate, but more studies are needed to fully evaluate its efficacy and safety. The pursuit of effective treatments for these challenging infections is a journey that requires a collaborative effort among researchers, clinicians, and patients.

Date :
  1. Date Completed 2017-12-27
  2. Date Revised 2018-02-05
Further Info :

Pubmed ID

27492531

DOI: Digital Object Identifier

10.1016/j.rmed.2016.06.015

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SNS
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in preparation
Languages

English

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