Safety and tolerability of once-daily tiotropium Respimat(®) as add-on to at least inhaled corticosteroids in adult patients with symptomatic asthma: A pooled safety analysis.

Author: BatemanEric D, BusseWilliam W, DahlRonald, DusserDaniel, EngelMichael, HalpinDavid, KerstjensHuib A M, Moroni-ZentgrafPetra, Zaremba-PechmannLiliana

Paper Details 
Original Abstract of the Article :
BACKGROUND: Tiotropium, a long-acting anticholinergic bronchodilator, has demonstrated efficacy and safety as add-on therapy to inhaled corticosteroids (ICS), with or without other maintenance therapies, in patients with symptomatic asthma. OBJECTIVE: To evaluate safety and tolerability of tiotropi...See full text at original site
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引用元:
https://doi.org/10.1016/j.rmed.2016.07.001

データ提供:米国国立医学図書館(NLM)

Safety and Tolerability of Tiotropium Respimat in Asthma

Asthma, a chronic respiratory condition, can be like traversing a desert landscape, with periods of calm and sudden bursts of turbulent winds. This research investigates the safety and tolerability of tiotropium Respimat, a long-acting anticholinergic bronchodilator, as add-on therapy to inhaled corticosteroids (ICS) in adults with symptomatic asthma. The authors pooled data from seven phase II and III randomized, double-blind, parallel-group trials, spanning treatment durations of 12-52 weeks. The study found that tiotropium Respimat demonstrated comparable safety and tolerability to placebo when used as add-on therapy to at least ICS. The most frequent adverse events were consistent with the disease profile, with the incidence of dry mouth, a common side effect of anticholinergics, being low. The findings suggest that tiotropium Respimat can be safely used as add-on therapy in adults with symptomatic asthma, offering a potential tool for managing this challenging respiratory condition.

Tiotropium Respimat: A Safe and Effective Tool for Asthma Management

The study demonstrates the safety and tolerability of tiotropium Respimat as add-on therapy for adults with symptomatic asthma. The findings suggest that this medication can be a valuable tool for managing asthma symptoms while minimizing potential risks.

Asthma Management: Finding the Right Balance

If you have asthma, it's essential to work with your healthcare provider to develop a personalized treatment plan that includes medication and lifestyle modifications. This may involve the use of inhaled corticosteroids, long-acting bronchodilators like tiotropium, and other therapies to manage your asthma effectively and prevent exacerbations.

Dr.Camel's Conclusion

This research explores the safety and tolerability of tiotropium Respimat as an add-on therapy for adults with asthma. The study provides reassurance that this medication can be used safely and effectively in combination with inhaled corticosteroids. The findings offer hope for individuals with asthma, providing a potential oasis in the midst of their respiratory journey. Just as a desert traveler must adapt to the changing landscape, individuals with asthma need a personalized approach to manage their condition, ensuring that they have the tools needed to navigate their respiratory journey with confidence and ease.

Date :
  1. Date Completed 2018-01-08
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27578478

DOI: Digital Object Identifier

10.1016/j.rmed.2016.07.001

Related Literature

SNS
PICO Info
in preparation
Languages

English

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