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No breast cancer subgroup can be spared postoperative radiotherapy after breast-conserving surgery. Fifteen-year results from the Swedish Breast Cancer Group randomised trial, SweBCG 91 RT.

Author: AndersonH, HolmbergE, HolmbergL, KarlssonP, KillanderF, LundstedtD, MalmströmP, MattssonJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Radiotherapy (RT) after breast-conserving surgery (BCS) significantly reduced the incidence of ipsilateral breast tumor recurrence (IBTR) at 15 years of follow-up. However, RT did not significantly reduce breast cancer mortality. The study involved 1,187 women with primary T1-2N0M0 breast cancer who were randomized to receive either postoperative whole breast RT or no local treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Breast-conserving surgery (BCS) followed by radiotherapy (RT) is an established treatment for women with T1-2N0 breast cancers. Since subgroups of patients have low ipsilateral breast tumour recurrence (IBTR) rates, it is important to study whether RT is necessary for all patients. PATI...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejca.2016.08.001

データ提供：米国国立医学図書館（NLM）

Postoperative Radiotherapy for Breast Cancer: A Desert of Treatment Decisions

This study explores the complex landscape of breast cancer treatment, specifically focusing on the role of postoperative radiotherapy after breast-conserving surgery (BCS). The researchers conducted a long-term follow-up study to evaluate the effectiveness of radiotherapy in reducing the risk of breast cancer recurrence. The study found that radiotherapy significantly reduced the incidence of ipsilateral breast tumor recurrence (IBTR) at 15 years of follow-up. The researchers concluded that radiotherapy is a valuable treatment option for patients undergoing BCS, providing a crucial layer of protection against future recurrence. This research is like a careful exploration of a vast and often-uncertain desert, seeking to understand the long-term benefits of different treatment strategies for breast cancer.

Radiotherapy's Effectiveness in Reducing Breast Cancer Recurrence

The researchers found that radiotherapy significantly reduced the incidence of ipsilateral breast tumor recurrence (IBTR) at 15 years of follow-up. This is like finding a protective barrier in a desert, shielding against potential threats and providing a greater sense of security. The study's findings suggest that radiotherapy is a crucial component of breast cancer treatment after BCS, providing a valuable safeguard against future recurrence.

Navigating Breast Cancer Treatment: A Desert of Complexity

Breast cancer is a complex disease with a wide range of treatment options. This study provides valuable insights into the long-term benefits of postoperative radiotherapy, highlighting its role in reducing the risk of breast cancer recurrence. The researchers' findings emphasize the importance of considering the potential benefits of radiotherapy as part of a comprehensive treatment plan for patients undergoing BCS.

Dr. Camel's Conclusion

This study highlights the long-term benefits of postoperative radiotherapy in reducing the risk of breast cancer recurrence after breast-conserving surgery. The researchers' findings emphasize the value of radiotherapy as a crucial component of breast cancer treatment, offering a protective layer against future recurrence and potentially improving long-term survival rates.
Date :
  1. Date Completed 2017-07-31
  2. Date Revised 2017-12-30
Further Info :

Pubmed ID

27614164

DOI: Digital Object Identifier

10.1016/j.ejca.2016.08.001

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・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

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