Paper Details 
Original Abstract of the Article :
AIM: To evaluate the antihypertensive efficiency and metabolic effects of controlled monotherapy with hydrochlorothiazide (HCT) and indapamide retard (IR) in hypertensive patients. SUBJECTS AND METHODS: The study included 50 patients with Stage II essential hypertension, grades 1-3 blood pressure (...See full text at original site
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引用元:
https://doi.org/10.17116/terarkh201688959-64

データ提供:米国国立医学図書館(NLM)

Diuretics: A Tale of Two Medications for Hypertension Management

Hypertension, often referred to as the silent killer, affects millions of people worldwide. Finding effective and safe treatment options is paramount for managing this condition. This study delves into the use of diuretic monotherapy for hypertension, comparing the efficacy and metabolic effects of two commonly used diuretics: hydrochlorothiazide (HCT) and indapamide retard (IR). The researchers conducted a study involving 50 patients with Stage II essential hypertension, analyzing the changes in blood pressure (BP), blood lipid levels, glucose levels, and potassium levels after 3 months of treatment with either HCT or IR. The results showed that both HCT and IR effectively normalized BP in over 50% of the patients. However, the study revealed a significant difference in the metabolic effects of the two medications.

Navigating the Desert of Hypertension: Finding the Right Medication

The study's findings, like a desert oasis offering respite from the relentless heat, provide valuable insights into the complexities of hypertension management. The researchers discovered that while both HCT and IR effectively lowered blood pressure, HCT had a detrimental impact on lipid and carbohydrate metabolism. This knowledge empowers healthcare professionals to make more informed decisions, considering the long-term metabolic implications of treatment options.

A Healthier Perspective on Hypertension: Choosing the Right Diuretic

Hypertension can pose a significant threat to overall health, and managing this condition effectively is crucial. This study sheds light on the impact of different diuretics on blood pressure and metabolic health. The findings underscore the importance of considering the long-term metabolic consequences of treatment options, especially for individuals at risk for cardiovascular disease or metabolic disorders.

Dr. Camel's Conclusion

This study, like a wise camel navigating the vast desert of hypertension, offers valuable insights into the intricacies of diuretic monotherapy. The researchers discovered that while both HCT and IR effectively lower blood pressure, HCT has a negative impact on lipid and carbohydrate metabolism. This knowledge serves as a valuable compass for healthcare professionals, enabling them to make more informed decisions about treatment options, ensuring the best possible outcomes for their patients.

Date :
  1. Date Completed 2017-02-23
  2. Date Revised 2019-02-21
Further Info :

Pubmed ID

27735915

DOI: Digital Object Identifier

10.17116/terarkh201688959-64

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PICO Info
in preparation
Languages

Russian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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