Paper Details 
Original Abstract of the Article :
Plants remain a major source of new drugs, leads and fine chemicals. Cell cultures deriving from plants offer a fascinating tool to study plant metabolic pathways and offer large scale production systems for valuable compounds - commercial examples include compounds such as paclitaxel. The major con...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044514/

データ提供:米国国立医学図書館(NLM)

Metabolic Stability of Engineered Hairy Roots

This study explores the long-term metabolic stability of

engineered hairy roots

, a type of plant cell culture used for producing valuable compounds. The researchers investigated the metabolic activity of hairy roots over a 16-year period, examining their genetic and metabolic stability after repeated subculturing. The study found that despite some fluctuation in metabolite yields, the hairy roots maintained significant metabolic activity over the long term, even after being subjected to prolonged subculturing. These findings suggest that engineered hairy roots can be a stable and reliable platform for large-scale production of valuable compounds, even over extended periods.

The Stability of Engineered Hairy Roots for Bioproduction

This study provides encouraging evidence for the long-term stability of engineered hairy roots, suggesting their suitability as a sustainable platform for producing valuable compounds. The researchers found that the hairy roots remained metabolically active and stable even after 16 years of subculturing, highlighting their potential for large-scale production processes. This study underscores the importance of investigating the long-term stability of cell cultures for bioproduction applications.

Implications for Plant-Based Biotechnology

This study sheds light on the potential of engineered hairy roots for sustainable production of valuable compounds. The researchers' findings suggest that hairy roots can provide a stable and reliable platform for bioproduction, even over extended periods. This research can contribute to the development of more efficient and sustainable approaches for producing pharmaceuticals and other valuable compounds using plant-based biotechnology.

Dr.Camel's Conclusion

Imagine a desert oasis, a haven for life and growth. Similarly, engineered hairy roots can thrive even in the face of prolonged subculturing, proving to be a sustainable and reliable source for valuable compounds. This study provides a glimpse into the potential of plant-based biotechnology to address growing global needs.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

27746806

DOI: Digital Object Identifier

PMC5044514

Related Literature

SNS
PICO Info
in preparation
Languages

English

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