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Is ovarian cancer a targetable disease? A systematic review and meta-analysis and genomic data investigation.

Author: BottaCirino, CagliotiFrancesca, ChiellinoSilvia, CilibertoDomenico, GiudiceTeresa Del, GualtieriSimona, PignataSandro, SalvinoAngela, StaropoliNicoletta, StrangioAlessandra, TagliaferriPierosandro, TassonePierfrancesco

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

While a combination of carboplatin, paclitaxel, and bevacizumab is the standard treatment for advanced ovarian cancer, there's still uncertainty about the role of targeted therapies. This study reviewed and analyzed research on targeted treatments for ovarian cancer to better understand their place in treatment plans.
Paper Details　
Original Abstract of the Article :
The current gold-standard for the first-line treatment in IIIb/IV stages of epithelial ovarian cancer (EOC) is the combination of carboplatin and paclitaxel plus bevacizumab in some countries. In the era of personalized medicine, there is still uncertainty on the impact of several molecularly target...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347729/

データ提供：米国国立医学図書館（NLM）

Ovarian Cancer: A Targetable Disease in the Era of Personalized Medicine

Ovarian cancer, a formidable foe, often lurks hidden within the body's intricate landscape. This study, like a detailed map revealing the complexities of this terrain, explores the potential of targeted therapy for ovarian cancer, a disease that can be challenging to treat.

The researchers, like skilled cartographers, delve into the world of personalized medicine, examining the effectiveness of various molecularly targeted agents in managing ovarian cancer. They conducted a systematic review and meta-analysis, providing a comprehensive overview of the current evidence.

The Promise of Personalized Medicine: Tailoring Treatment to the Individual

This study, like a compass guiding us toward more effective treatments, highlights the promise of personalized medicine in ovarian cancer management. By understanding the unique molecular characteristics of each tumor, we can develop more targeted therapies that are more effective and less toxic.

Hope on the Horizon: New Strategies for a Complex Disease

The desert of ovarian cancer can be a daunting landscape, but this study offers hope by showcasing the potential of personalized medicine. The findings suggest that by tailoring treatment to the individual, we can improve outcomes and create a more hopeful future for those affected by this challenging disease.

Dr.Camel's Conclusion

The fight against ovarian cancer requires innovative strategies, and this study provides valuable insights into the potential of personalized medicine. By understanding the unique molecular characteristics of each tumor and developing targeted therapies, we can pave the way for more effective and less toxic treatments, offering hope for a brighter future.

Date :
  1. Date Completed 2018-02-21
  2. Date Revised 2023-11-12
Further Info :

Pubmed ID

27764790

DOI: Digital Object Identifier

PMC5347729

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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