Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKα and downregulation of STAT3 and caspase 3 dependent apoptotic pathways.

Author: AfrinMst Rejina, ArumugamSomasundaram, HarimaMeilei, KaruppagounderVengadeshprabhu, MiyashitaShizuka, NakamuraTakashi, RahmanMd Azizur, SreedharRemya, SuzukiHiroshi, SuzukiKenji, UenoKazuyuki, WatanabeKenichi

Paper Details 
Original Abstract of the Article :
Le Carbone (LC) is a charcoal supplement, which contains a large amount of dietary fibers. Several studies suggested that charcoal supplement may be beneficial for stomach disorders, diarrhea, gas and indigestion. But no studies address whether LC intake would suppress inflammation, cell proliferati...See full text at original site
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引用元:
https://doi.org/10.1016/j.intimp.2016.10.023

データ提供:米国国立医学図書館(NLM)

Le Carbone: A Charcoal Supplement with Potential for Colitis Treatment

Inflammatory bowel disease (IBD), a chronic condition affecting the digestive tract, can be a challenging experience for many. This study investigates the potential therapeutic benefits of Le Carbone, a charcoal supplement, in the treatment of colitis, a common form of IBD.

Le Carbone: A Potential Ally in the Fight Against Colitis

The study demonstrates the ability of Le Carbone to reduce inflammation and apoptosis in mice with colitis. The researchers found that Le Carbone effectively attenuated the severity of colitis, suggesting its potential as an adjuvant therapy for IBD. It's like a camel finding a nourishing herb in the desert, providing relief and support in a challenging environment.

Navigating the Desert of IBD Treatment

This research highlights the need for continued exploration of alternative and complementary therapies for IBD. The study suggests that Le Carbone could potentially play a role in managing colitis, but further research is needed to confirm its efficacy and safety in humans. It's like a camel discovering a new source of water in the desert – we need to carefully evaluate its potential before relying on it.

Dr.Camel's Conclusion

This study presents intriguing evidence for the potential therapeutic benefits of Le Carbone in the treatment of colitis. It's a reminder that the world of medicine is constantly evolving, and new therapies are continually emerging. Just like a camel adapting to the ever-changing desert landscape, we need to embrace a spirit of discovery and innovation in our pursuit of better health outcomes for all.

Date :
  1. Date Completed 2017-04-11
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

27978459

DOI: Digital Object Identifier

10.1016/j.intimp.2016.10.023

Related Literature

SNS
PICO Info
in preparation
Languages

English

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