Effective treatment of stomach disorders: A Synthesis of Findings from 28 Studies

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Original Abstract of the Article

Key research findings

Several studies suggest that certain herbs and foods may be helpful in treating stomach disorders. For example, 10 reports that an ethanol extract of Leonurus sibiricus L. showed gastroprotective effects in mice. 25 found that Le Carbone, a charcoal supplement, modulated dextran sulfate sodium (DSS)-induced acute colitis in mice. Additionally, 19 indicated that Cuphea ignea extract had a gastroprotective effect against ethanol-induced gastric ulcers in rats.

On the other hand, 9 points out the potential impact of Weifuchun, a Chinese herbal prescription, on intestinal microbiota changes in patients with precancerous lesions of gastric cancer. 8 suggests that clove (Syzygium aromaticum) may inhibit the growth of Helicobacter pylori, a bacterium linked to various gastric diseases.

These studies indicate the potential of natural substances and traditional Chinese medicines in treating stomach disorders. However, further research is required to confirm their effectiveness in human stomach diseases.

treatment summary

An ethanol extract of Leonurus sibiricus L. showed potential gastroprotective effects in mice, as reported in 10 . Le Carbone, a charcoal supplement, demonstrated the ability to modulate dextran sulfate sodium (DSS)-induced acute colitis in mice, according to 25 . 19 showed that Cuphea ignea extract had a gastroprotective effect against ethanol-induced gastric ulcers in rats.

Weifuchun, a Chinese herbal prescription, was suggested to influence intestinal microbiota changes in patients with precancerous lesions of gastric cancer, as indicated in 9 . 8 suggested that clove (Syzygium aromaticum) might inhibit the growth of Helicobacter pylori, a bacterium linked to various gastric diseases.

Benefits and Risks

Benefit Summary

Several studies indicate the potential of certain herbs and foods in treating stomach disorders. For instance, an ethanol extract of Leonurus sibiricus L. might offer gastroprotection. Le Carbone, a charcoal supplement, could potentially help manage colitis. Cuphea ignea extract might be beneficial for treating gastric ulcers.

Weifuchun, a Chinese herbal prescription, may impact intestinal microbiota in patients with precancerous lesions of gastric cancer. Clove (Syzygium aromaticum) might help inhibit the growth of Helicobacter pylori, a bacterium linked to various gastric diseases.

Risk Summary

The safety and efficacy of these herbs and foods haven't been fully investigated yet. Therefore, consulting a doctor before consuming them is crucial.

Comparison of Research

Similarities in Research

These studies collectively suggest that natural substances and traditional Chinese medicines may offer potential benefits in treating stomach disorders.

Differences in Research

These studies differ in terms of the specific diseases targeted, the substances and traditional medicines used, the research methodologies, and the results obtained.

Consistency and Contradictions in Results

The results of these studies are not always consistent. For example, while some research indicates the gastroprotective effects of an ethanol extract of Leonurus sibiricus L. other studies may not confirm this effect.

Applying Findings to Daily Life: Cautions

Directly applying these research findings to everyday life is not recommended. Consulting a doctor before consuming any of these herbs or foods is essential. Additionally, consider the potential for interactions with other medications.

Limitations of Current Research

These studies are still limited in scope. To determine the effectiveness of these herbs and foods for human stomach diseases, further research is necessary.

Future Research Directions

Clinical trials involving humans are needed to investigate the specific effects of these herbs and foods on stomach disorders. Research on potential interactions with other medications should also be conducted.

Conclusion

Certain studies suggest that specific herbs and foods might be helpful in treating stomach disorders. However, more research is needed to validate their effectiveness in humans. Consult a doctor before incorporating these substances into your diet.

List of treatments

Ethanol extract of Leonurus sibiricus L. Le Carbone, Cuphea ignea extract, Weifuchun, Clove (Syzygium aromaticum)

Literature analysis of 28 papers
Positive Content
24
Neutral Content
3
Negative Content
1
Article Type
3
0
1
5
28
1.

Taste and Smell Disorders in Cancer Treatment: Results from an Integrative Rapid Systematic Review.

Author: Buttiron WebberTania, BriataIrene Maria, DeCensiAndrea, CevascoIsabella, PaleariLaura

TSD treatment

Changes in taste and smell are common side effects of cancer treatments, impacting a patient's quality of life. This review identified several cancer drugs that frequently cause these problems, including docetaxel, paclitaxel, capecitabine, cyclophosphamide, and others. The study found that taste problems occurred in 17-86% of patients, while smell problems affected 8-45%. Further research is needed to better understand and prevent these side effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

2.

[The diagnosis and treatment of functional stomach disorders].

Author: Mal'tsevL M, BarbulevV U, KobzevV P

Stomach disorder treatment

This article focuses on a system for diagnosing, treating, and rehabilitating servicemen with functional stomach disorders. The recommended staged rehabilitation approach incorporates physical, dietetic, psychological, physiotherapeutic, and medical interventions.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Russian

3.

Inhibitory and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa phytochemical compounds on human α-glucosidases.

Author: NyathiBrilliant, BvunzawabayaJonathan Tatenda, Venissa P MudawarimaChido, ManzombeEmily, TsotsoroKudakwashe, SelemaniMajor Allen, MunyukiGadzikano, RwereFreeborn

This study investigates the inhibitory effect of Xeroderris stuhlmannii, a medicinal plant traditionally used in Zimbabwe to treat type 2 diabetes mellitus, against digestive enzymes. The study aims to provide scientific evidence to support its traditional use.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

4.

Exploring the relationship between intestinal flora and the pathological mechanism of myopia in adolescents from the perspective of Chinese and Western medicine: A review.

Author: XiXiaoming, HanLiang, DingMengmeng, LiJinglu, QiaoChenye, LiuZongjian, QieShuyan

Adolescent myopia
Intestinal flora impact

This abstract explores the potential link between intestinal flora and adolescent myopia. It reviews the pathological mechanisms of myopia in modern medicine and traditional Chinese medicine, highlighting the importance of a holistic approach to prevention and treatment.

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

7.

Gastroprotective effect of low dose Eugenol in experimental rats against ethanol induced toxicity: Involvement of antiinflammatory and antioxidant mechanism.

Author: HobaniYahya Hasan, MohanSyam, ShaheenEmad, AbdelhaleemAymen, Faruque AhmadMd, BhatiaSaurabh, Abou-ElhamdAlaa Sayed

Ulcer protection
Ulcer worsening

Clove oil, containing eugenol as its main component, has traditional uses for stomach disorders. While eugenol has shown gastroprotective effects, its precise mechanism is not fully understood. This review explores the complex effects of eugenol on ulcer protection, highlighting its potential benefits at lower doses and detrimental effects at higher doses.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

8.

In vitro anti-Helicobacter pylori activity of Syzygium aromaticum and the preliminary mechanism of action.

Author: PengChang, SangShuyi, ShenXue, ZhangWeijia, YanJiahui, ChenPengting, JiangCheng, YuanYuemei, ZhuWeixing, YaoMeicun

Anti-H. pylori activity

Clove is a spice that has been used in traditional medicine. This study suggests that clove may be helpful for treating H. pylori, a bacteria that causes stomach problems.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Validation StudyResearch to assess the validity and reliability of new measurement methods or diagnostic tests.

Language : English

9.

A correlational study of Weifuchun and its clinical effect on intestinal flora in precancerous lesions of gastric cancer.

Author: BianYanqin, ChenXi, CaoHongyan, XieDong, ZhuMeiping, YuanNong, LuLu, LuBingjie, WuChao, Bahaji AzamiNisma Lena, WangZheng, WangHuijun, ZhangYeqing, LiKun, YeGuan, SunMingyu

Treat stomach disorders

The effect of Weifuchun (WFC), a Chinese herbal prescription, on intestinal microbiota changes in precancerous lesions of gastric cancer (PLGC) patients will be investigated.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

10.

Gastroprotective action of the ethanol extract of Leonurus sibiricus L. (Lamiaceae) in mice.

Author: BianoLaiza S, OliveiraAlan S, PalmeiraDavid N, SilvaLuis André, de Albuquerque-JuniorRicardo L C, DuarteMarcelo C, CorreaCristiane B, GrespanRenata, BatistaJosemar S, CamargoEnilton A

Gastroprotective action

Ethanol extract of Leonurus sibiricus (EELs) showed gastroprotective action in mice by reducing gastric ulcers, lipoperoxidation, and increasing sulfhydryl content in the stomach.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

11.

Catharanthus roseus (L.) G. Don: A review of its ethnobotany, phytochemistry, ethnopharmacology and toxicities.

Author: KumarSunil, SinghBikarma, SinghRamesh

Cancer treatment
Diabetes treatment
Stomach disorders treatment

Catharanthus roseus (L.) G. Don, a medicinal plant, is traditionally used for various medical purposes, including cancer treatment. Its anticancer properties are attributed to bisindole alkaloids, such as vinblastine, vincristine, and vindesine.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

13.

Retrospective Study on the Pattern of Off-label Use of Misoprostol in Tabuk, Saudi Arabia.

Author: AlharthiNouf M, AlsaeedMohannad Sahaw, AlsharifMohammed Omar, AlmalkiMohammed Ghabbash, AlshehriWael Saeed, PrabaharKousalya

Intrauterine device insertion
Labor induction
Morbidity
Mortality

This research investigated the percentage of morbidity and mortality associated with off-label use of misoprostol, identifying the most common off-label uses in Tabuk hospitals. The study also assessed the availability of policies and procedures regarding off-label misoprostol prescribing.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

14.

The genus Nepeta: Traditional uses, phytochemicals and pharmacological properties.

Author: SharmaAjay, CooperRaymond, BhardwajGarima, CannooDamanjit Singh

Treatment for various ailments

This review provides a comprehensive overview of the traditional uses, pharmacology, phytochemistry, and toxicology of Nepeta species. The review emphasizes encouraging research towards the pharmaceutical applications of Nepeta.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

16.

[Therapeutic effect of herb-separated moxibustion at Jinsuo (GV 8)-eight-diagram points on diarrhea-type irritable bowel syndrome of liver stagnation and spleen deficiency].

Author: HaoLi-Jun, ShiZhi-Min

IBS-D treatment

This study investigated the clinical therapeutic effect of herb-separated moxibustion at Jinsuo (GV 8)- eight-diagram points on diarrhea-type irritable bowel syndrome (IBS-D) of liver stagnation and spleen deficiency. Moxibustion was compared with oral administration of pinaverium bromide tablets and Chinese herbal decoction.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : Chinese

17.

[Effect of herb-partitioned moxibustion at <i>fanwei</i> point on plasma motilin and serum gastrin in patients of diabetic gastroparesis].

Author: MengNa, ShiZhi-Min

Diabetic gastroparesis treatment
TCM symptom reduction

A randomized controlled trial of 134 patients with diabetic gastroparesis found that herb-partitioned moxibustion at "Zusanli" (ST36) and "Zhongwan" (CV12) was effective in improving gastrointestinal motility and reducing symptoms.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : Chinese

19.

Antiulcerogenic effect of Cuphea ignea extract against ethanol-induced gastric ulcer in rats.

Author: MousaAmria M, El-SammadNermin M, HassanSherien K, MadboliAbd El Nasser A, HashimAmani N, MoustafaEman S, BakrySherien M, ElsayedElsayed A

Gastropreventive effect

This study evaluated the gastroprotective effect of an aqueous ethanolic extract of Cuphea ignea aerial parts on ethanol-induced gastric ulcer.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

22.

Anti-ulcerogenic activity of dentatin from clausena excavata Burm.f. against ethanol-induced gastric ulcer in rats: Possible role of mucus and anti-oxidant effect.

Author: SidahmedHeyam Mohamed Ali, VadiveluJamuna, LokeMun Fai, ArbabIsmail Adam, AbdulBustamam, SukariMohd Aspollah, AbdelwahabSiddig Ibrahim

Anti-ulcer activity
Gastro-protective activity

Dentatin, isolated from Clausena excavata Burm.f., possessed gastroprotective activity due to its anti-secretory, mucus production, antioxidant, and HSP70 activities.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

23.

[Therapeutic effects of the integrated acupuncture and Chinese herbal medicine on reflux esophagitis].

Author: ZhangWan, LiBolin, SunJianhui, WangZhikun, ZhangNana, ShiFang, PeiLin

Improved reflux esophagitis treatment

This study compared the clinical therapeutic effects of combined therapy of *huazhuo jiedu jiangni* decoction and acupuncture, omeprazole and Chinese herbal medicine on reflux esophagitis.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : Chinese

24.

Toxins and pharmacologically active compounds from species of the family Bufonidae (Amphibia, Anura).

Author: RodríguezCandelario, Rollins-SmithLouise, IbáñezRoberto, Durant-ArchiboldArmando A, GutiérrezMarcelino

Cancer treatment

The Bufonidae family, containing 15 of the 47 amphibian species used in traditional medicines, holds significant potential for pharmacological and natural products research. Asian and American tribes utilize the skin and parotoid gland secretions of certain toads for treating hemorrhages, venomous animal bites and stings, skin and stomach disorders, and various cancers.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

25.

Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKα and downregulation of STAT3 and caspase 3 dependent apoptotic pathways.

Author: AfrinMst Rejina, ArumugamSomasundaram, RahmanMd Azizur, KaruppagounderVengadeshprabhu, SreedharRemya, HarimaMeilei, SuzukiHiroshi, NakamuraTakashi, MiyashitaShizuka, SuzukiKenji, UenoKazuyuki, WatanabeKenichi

Colitis treatment

Le Carbone (LC), a charcoal supplement, was found to significantly attenuate inflammation and apoptosis in mice with colitis, suggesting its potential as an adjuvant treatment for inflammatory bowel disease.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

27.

Evidence of anti-inflammatory and antinociceptive activities of Plinia edulis leaf infusion.

Author: AzevedoLara F, SilvaSimone Maria da, NavarroLucas B, YamaguchiLydia F, NascimentoCarlos Giovani O, SonciniRoseli, IshikawaTati

Anti-inflammatory activity
Antinociceptive activity

The study explores the anti-inflammatory and antinociceptive activity of Plinia edulis leaf infusion in mice. The findings suggest that the infusion possesses potential therapeutic benefits for the treatment of inflammatory and pain conditions.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

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