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Evaluation of anxiolytic effects of aripiprazole and hydroxyzine as a combination in mice.
Author: KalePravin Popatrao, SavaiJay, SawantdesaiNikita Shekhar
Original Abstract of the Article :
CONTEXT: Anxiety disorders are chronic, common, and often comorbid. There is an unmet need in its treatment. Aripiprazole and hydroxyzine are well-known therapeutic options used as monotherapy in clinics. They have different mechanisms and site of actions. AIM: The objective of the present study wa...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153890/
データ提供:米国国立医学図書館(NLM)
Aripiprazole and Hydroxyzine: A Team Effort for Anxiety
Anxiety disorders are like a relentless sandstorm in the desert of the human mind, making it difficult to see clearly and move forward. This study examines the potential benefits of combining aripiprazole and hydroxyzine in the treatment of anxiety. Imagine two seasoned desert travelers, each with unique skills, combining their expertise to navigate the treacherous landscape. The researchers explore how these two medications can work together to combat anxiety.
Aripiprazole and Hydroxyzine: A Synergy for Anxiety Relief
The study found that combining aripiprazole and hydroxyzine in a specific ratio (0.5 mg/kg aripiprazole + 1.5 mg/kg hydroxyzine) provided a better anxiolytic effect compared to aripiprazole alone. This suggests that the combination of these medications may offer a more comprehensive approach to treating anxiety, addressing multiple aspects of this complex condition. This research provides a hopeful glimpse into the potential for improved anxiety management through a multi-pronged approach.
Finding the Right Balance for Anxiety Relief
While this study suggests the potential benefits of combining aripiprazole and hydroxyzine, it's important to remember that medication dosage and treatment plans should be individualized. Just as a camel needs to find the right balance of water and food to survive in the desert, individuals with anxiety need to work with a healthcare professional to find the right combination of treatments for their specific needs.
Dr.Camel's Conclusion
This research reminds us that anxiety is a complex condition requiring a comprehensive approach to treatment. The combination of aripiprazole and hydroxyzine shows promise for effectively managing anxiety, offering a more holistic approach to tackling this challenging mental health issue. Like a skilled caravan leader navigating the desert, healthcare providers must continue to explore new and innovative ways to combat anxiety, ensuring the well-being of those affected.
Date :
- Date Completed n.d.
- Date Revised 2020-10-01
Further Info :
Related Literature
English
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