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Lymphocyte immunotherapy in the treatment of recurrent miscarriage: systematic review and meta-analysis.

Author: Araujo JúniorEdward, BariniRicardo, CavalcanteMarcelo Borges, Da Silva CostaFabricio, SarnoManoel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This research explores the use of immunotherapy in cases of recurrent miscarriage (RM). The study discusses the potential role of immunologic factors in RM and investigates the efficacy and safety of immunotherapy.
Paper Details　
Original Abstract of the Article :
Recurrent miscarriage (RM) affects up to 2-3% of couples of reproductive age. There are several causes for this condition, including immunologic. The embryo is considered an allograft, subject to the rejection mechanisms of the maternal immune system. Immunotherapy involving immunization with lympho...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s00404-016-4270-z

データ提供：米国国立医学図書館（NLM）

Lymphocyte Immunotherapy in the Treatment of Recurrent Miscarriage: Systematic Review and Meta-Analysis

Recurrent miscarriage (RM), the experience of two or more consecutive pregnancy losses, affects a significant number of couples. While there are various causes of RM, including genetic, hormonal, and uterine factors, immunologic factors have also been implicated. Lymphocyte immunotherapy, a treatment that involves injecting the mother with lymphocytes, is sometimes considered for women with idiopathic RM, but its effectiveness and safety remain controversial.

Lymphocyte Immunotherapy for Recurrent Miscarriage: Inconclusive Evidence

This systematic review and meta-analysis aimed to evaluate the effectiveness and safety of lymphocyte immunotherapy for RM. The results were inconclusive, with conflicting findings across different studies. The review highlights the need for further well-designed studies to determine whether lymphocyte immunotherapy is an effective treatment for RM.

Navigating the Desert of Recurrent Miscarriage: Seeking Answers

Recurrent miscarriage is a heartbreaking experience that can feel like a never-ending journey through a vast desert of uncertainty. This research highlights the need for more rigorous research into the effectiveness of lymphocyte immunotherapy for RM. It underscores the importance of finding reliable solutions to help couples achieve their dream of parenthood.

Dr.Camel's Conclusion

As a researcher with a deep empathy for couples struggling with recurrent miscarriage, I'm continually searching for answers in the vast desert of reproductive health. While the evidence on lymphocyte immunotherapy remains inconclusive, this research highlights the urgent need for further investigation to provide better treatment options for those facing this challenging experience. We must continue to explore new paths and seek oases of hope for couples hoping to build their families.
Date :
  1. Date Completed 2017-08-17
  2. Date Revised 2023-09-06
Further Info :

Pubmed ID

28004193

DOI: Digital Object Identifier

10.1007/s00404-016-4270-z

Related Literature

Article Analysis
・Effective treatment of miscarriage
SNS
PICO Info
in preparation
Languages

English

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