Paper Details 
Original Abstract of the Article :
Zidovudine (ZDV) has been associated with risk of haematological toxicity. Safety data from clinical trials is generally limited to 48 weeks. We assessed the short- and mid-term toxicity of ZDV/lamivudine (3TC) fixed-dose combination scored tablets in HIV-infected children followed in the European P...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350228/

データ提供:米国国立医学図書館(NLM)

Zidovudine/Lamivudine: Safety in Children with HIV Infection

This research examines the safety of zidovudine/lamivudine (ZDV/3TC), a common combination therapy for HIV infection in children. The study investigates the short- and mid-term toxicity of this medication in a large cohort of children enrolled in the European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) network. The authors found that ZDV/3TC was generally safe and well-tolerated in children, with limited haematological toxicity observed. This research provides valuable insights into the safety profile of this important HIV treatment.

Ensuring the Safety of HIV Treatment in Children

This study emphasizes the importance of understanding the safety profile of HIV medications in children. It's like carefully navigating a desert oasis – knowing the potential risks and benefits of each route is essential for ensuring a safe and successful journey. The research provides reassurance about the safety of ZDV/3TC in children, but highlights the need for ongoing monitoring and careful assessment of potential side effects.

The Importance of Long-Term Monitoring

This research underscores the importance of long-term monitoring of HIV patients, particularly children, who are receiving antiretroviral therapy. It's like tending a delicate desert garden – regular observation and adjustments are necessary to ensure its continued health and growth. The study's findings highlight the importance of ongoing research into the safety and efficacy of HIV treatments, particularly for vulnerable populations like children.

Dr.Camel's Conclusion

This research provides a reassuring outlook on the safety of ZDV/3TC in children with HIV. It's like finding a reliable water source in a vast desert – this research offers hope and confidence for those seeking effective and safe HIV treatment for their children.

Date :
  1. Date Completed 2017-04-17
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

28028587

DOI: Digital Object Identifier

PMC5350228

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Languages

English

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