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Post-treatment control or treated controllers? Viral remission in treated and untreated primary HIV infection.

Author: , FidlerSarah, FraterJohn, GossezMorgane, GoulderPhilip, LeitmanEllen M, MartinGenevieve E, MeyerowitzJodi, PorterKholoud, StöhrWolfgang, WilliamsJames P

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A cure for HIV means being able to stop antiretroviral therapy (ART) without the virus returning. To understand how well new treatments for HIV cure work, it's essential to know how well the body naturally controls the virus and how ART affects the virus after treatment is stopped.
Paper Details　
Original Abstract of the Article :
An HIV cure will impose aviraemia that is sustained following the withdrawal of antiretroviral therapy (ART). Understanding the efficacy of novel interventions aimed at curing HIV requires characterization of both natural viral control and the effect of ART on viral control after treatment interrupt...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278888/

データ提供：米国国立医学図書館（NLM）

HIV Cure: A Long and Winding Desert Road

The quest for an HIV cure, like a journey across a vast and unforgiving desert, is a complex and challenging undertaking. This research examines the nature of viral control in both treated and untreated individuals with primary HIV infection. The authors investigated the potential for achieving sustained virological remission following the withdrawal of antiretroviral therapy (ART). Their findings highlight the challenges associated with achieving a durable HIV cure, emphasizing the need for innovative approaches to target viral reservoirs and enhance immune function.

HIV Cure: A Long and Winding Desert Road

The study's findings underscore the complexities of achieving a durable HIV cure. Just as a traveler in the desert faces many obstacles, researchers are grappling with the challenge of eradicating HIV from the body. The study highlights the need for continued research and development of new strategies to achieve this elusive goal.

Staying Hydrated in the Desert of HIV

HIV, like a relentless desert heat, requires ongoing management and vigilance. Maintaining a healthy lifestyle, including a balanced diet, regular exercise, and stress management techniques, can play a significant role in supporting overall health and immune function. Just as a traveler in the desert needs to stay hydrated, individuals with HIV need to prioritize their health and consult with healthcare professionals to develop a personalized management plan.

Dr.Camel's Conclusion

This research reminds us that the journey towards an HIV cure is a long and arduous one. It highlights the need for continued scientific exploration and collaboration to develop innovative approaches that can effectively combat this persistent virus. Just as a camel can adapt to the harsh desert environment, we can learn to leverage our knowledge and resources to find solutions that can ultimately lead to an HIV cure.

Date :
  1. Date Completed 2018-01-02
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

28060012

DOI: Digital Object Identifier

PMC5278888

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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