Penbutolol, a new non-selective beta-adrenergic blocking compound in the treatment of hypertension. A comparision with propranolol.

Author: FrickM H, HartikainenM, PörstiP

Paper Details 
Original Abstract of the Article :
The antihypertensive effect of a new non-selective beta-adrenergic blocking compound, penbutolol (40 mg b.i.d.), was compared with propranolol (160 mg b.i.d.) in a series of 20 hypertensive patients using a double-blind cross-over scheme. Both compounds reduced both the supine and the standing blood...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/28071

データ提供:米国国立医学図書館(NLM)

Penbutolol: A New Player in the Hypertension Game

Hypertension, a silent threat lurking in the shadows, affects millions worldwide. This study focuses on penbutolol, a new non-selective beta-adrenergic blocking compound, and compares its effectiveness in managing hypertension to the well-established drug propranolol. The authors conducted a double-blind cross-over study to meticulously assess the blood pressure-lowering effects of both medications. Their findings demonstrate that penbutolol is a promising contender in the field of hypertension management.

Penbutolol: A New Contender in Hypertension Treatment

The study found that penbutolol effectively reduced both supine and standing blood pressure, demonstrating its potential for controlling hypertension. Notably, its efficacy was comparable to propranolol, indicating that it could be a viable alternative. The authors also observed that both medications effectively lowered heart rate, a key factor in managing hypertension.

Penbutolol: A Promising Avenue for Hypertension Control

This research highlights the potential of penbutolol as a new and effective treatment option for hypertension. Further research is necessary to fully understand its long-term efficacy and safety profile.

Dr.Camel's Conclusion

Imagine a desert where the wind whispers secrets of high blood pressure. Penbutolol, a new player in the hypertension game, emerges like a cool breeze. This study shows it has the potential to control blood pressure effectively, but as with any new discovery in the vast desert of medicine, further research is crucial to ensure its safety and effectiveness for the long haul.

Date :
  1. Date Completed 1978-09-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

28071

DOI: Digital Object Identifier

28071

Related Literature

SNS
PICO Info
in preparation
Languages

English

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