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[Ovarian Ablation in Breast Cancer Patients and the Possibility of Influencing Treatment Side Effects].

Author: PalácováM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Ovarian suppression or ablation used for breast carcinoma treatment can induce temporary or permanent menopause, leading to menopausal symptoms like hot flashes, vaginal atrophy, and sleep disturbances. Other common side effects include decreased bone density, mood swings, and depression. Since hormone replacement therapy is contraindicated in breast cancer patients, management involves non-hormonal pharmacological and non-pharmacological methods. Non-pharmacological options include cooling techniques, acupuncture, and cognitive behavioral therapy. Pharmacological options include antidepressants like SSRIs and SNRIs, gabapentin, pregabalin, and paroxetine, which has FDA approval for hot flashes. Management of vaginal atrophy involves topical lubricants and, in severe cases, short-term topical estrogens. Multidisciplinary approaches are recommended for managing these complex symptoms.
Paper Details　
Original Abstract of the Article :
Ovarian suppression or ovarian ablation used in treatment of breast carcinoma results in temporary or permanent menopause and associated menopausal symptoms - most frequently vasomotoric symptoms (hot flashes, sweats), vaginal atrophy, sleep disturbances. Patients can also experience frequent decrea...See full text at original site
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引用元：
https://doi.org/10.14735/amko20163S29

データ提供：米国国立医学図書館（NLM）

Ovarian Ablation in Breast Cancer: Managing Treatment Side Effects

Ovarian suppression or ablation, a common treatment approach for breast cancer, can lead to menopausal symptoms, resembling the dry and harsh conditions of a desert environment. This study, like a guidebook for navigating the desert of postmenopausal challenges, explores the management of these side effects, including vasomotoric symptoms (hot flashes, sweats), vaginal atrophy, sleep disturbances, and bone density changes. The researchers, like seasoned desert travelers, provide practical advice and highlight the importance of multidisciplinary care in addressing these complex issues.

Navigating the Desert of Menopausal Symptoms

The researchers emphasize that hormonal replacement therapy is contraindicated in women with breast cancer, leaving alternative options like non-hormonal medications and lifestyle modifications. They recommend a multidisciplinary approach, involving healthcare professionals, therapists, and support groups, to help women navigate the challenges of menopause. This approach, like a well-equipped caravan, provides comprehensive support and guidance to address the diverse needs of women facing these changes.

A Multidisciplinary Oasis of Support

This study highlights the need for a multidisciplinary approach to managing the side effects of ovarian ablation. Like a desert oasis providing respite and resources, a multidisciplinary team can offer a range of therapies, including non-hormonal medications, cognitive behavioral therapy, and lifestyle modifications, to alleviate symptoms and improve quality of life.

Dr.Camel's Conclusion

The desert of menopause can be a challenging landscape, but this study, like a compass guiding us through the arid terrain, offers valuable insights into the management of side effects associated with ovarian ablation. The researchers, like skilled desert guides, emphasize the importance of a multidisciplinary approach, providing a comprehensive oasis of support for women facing these challenges. By understanding and addressing these issues, we can help women navigate this desert with greater confidence and well-being.

Date :
  1. Date Completed 2018-10-24
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

28118722

DOI: Digital Object Identifier

10.14735/amko20163S29

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