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Anthelmintic Potential of Thymoquinone and Curcumin on Fasciola gigantica.
Author: AbidiS M A, KhanAsad U, KhanM A Hannan, KhanShahper N, KhanYasir A, RehmanAbdur, RehmanLubna, UllahRizwan, ZafeerMohd Faraz
Original Abstract of the Article :
Fasciolosis an economically important global disease of ruminants in the temperate and tropical regions, caused by Fasciola hepatica and F. gigantica, respectively, also poses a potential zoonotic threat. In India alone it causes huge losses to stakeholders. Anthelmintics including triclabendazole h...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289557/
データ提供:米国国立医学図書館(NLM)
Thymoquinone and Curcumin: New Anthelmintic Weapons Against Fasciolosis
The fight against fasciolosis, a parasitic disease impacting livestock and humans, is a constant battle. This study explores the potential of two natural compounds, thymoquinone and curcumin, as anthelmintic agents. Like resourceful desert nomads seeking alternative sources of sustenance, researchers investigate these plant-derived compounds as potential weapons against the parasitic flukes that cause fasciolosis. The study's findings offer promising insights into the anthelmintic potential of these natural compounds.
Thymoquinone and Curcumin: Promising Anthelmintic Potential
Both thymoquinone and curcumin demonstrated significant anthelmintic effects in vitro. They reduced worm motility, disrupted the parasite's tegument, and inhibited the activity of key enzymes involved in detoxification and virulence. These findings suggest that these compounds may have potential as novel anthelmintic agents for the control of fasciolosis.
A Natural Approach to Parasitic Control
This study highlights the potential of natural compounds like thymoquinone and curcumin in combating parasitic diseases. These compounds offer a promising alternative to synthetic anthelmintics, which are often plagued by issues of resistance. Further research is needed to evaluate their effectiveness and safety in vivo, but these findings offer a glimmer of hope in the battle against fasciolosis.
Dr. Camel's Conclusion
This study is like a desert oasis offering a respite from the scorching heat of parasitic infection. Thymoquinone and curcumin, these natural treasures, show promise as potential weapons against fasciolosis. While more research is needed, these findings encourage us to continue exploring the vast desert of natural compounds for new solutions to health challenges.
Date :
- Date Completed 2017-08-21
- Date Revised 2019-02-08
Further Info :
Related Literature
English
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