Paper Details 
Original Abstract of the Article :
Fasciolosis an economically important global disease of ruminants in the temperate and tropical regions, caused by Fasciola hepatica and F. gigantica, respectively, also poses a potential zoonotic threat. In India alone it causes huge losses to stakeholders. Anthelmintics including triclabendazole h...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289557/

データ提供:米国国立医学図書館(NLM)

Thymoquinone and Curcumin: New Anthelmintic Weapons Against Fasciolosis

The fight against fasciolosis, a parasitic disease impacting livestock and humans, is a constant battle. This study explores the potential of two natural compounds, thymoquinone and curcumin, as anthelmintic agents. Like resourceful desert nomads seeking alternative sources of sustenance, researchers investigate these plant-derived compounds as potential weapons against the parasitic flukes that cause fasciolosis. The study's findings offer promising insights into the anthelmintic potential of these natural compounds.

Thymoquinone and Curcumin: Promising Anthelmintic Potential

Both thymoquinone and curcumin demonstrated significant anthelmintic effects in vitro. They reduced worm motility, disrupted the parasite's tegument, and inhibited the activity of key enzymes involved in detoxification and virulence. These findings suggest that these compounds may have potential as novel anthelmintic agents for the control of fasciolosis.

A Natural Approach to Parasitic Control

This study highlights the potential of natural compounds like thymoquinone and curcumin in combating parasitic diseases. These compounds offer a promising alternative to synthetic anthelmintics, which are often plagued by issues of resistance. Further research is needed to evaluate their effectiveness and safety in vivo, but these findings offer a glimmer of hope in the battle against fasciolosis.

Dr. Camel's Conclusion

This study is like a desert oasis offering a respite from the scorching heat of parasitic infection. Thymoquinone and curcumin, these natural treasures, show promise as potential weapons against fasciolosis. While more research is needed, these findings encourage us to continue exploring the vast desert of natural compounds for new solutions to health challenges.

Date :
  1. Date Completed 2017-08-21
  2. Date Revised 2019-02-08
Further Info :

Pubmed ID

28152102

DOI: Digital Object Identifier

PMC5289557

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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