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Live attenuated varicella vaccine in healthy 12- to 24-month-old children.
Author: FattlarD, JohnsonC E, KumarM L, RomeL P, ShurinP A
Original Abstract of the Article :
We studied live attenuated Oka/Merck varicella vaccine in 147 seronegative children 12 to 24 months of age and their 94 seronegative older siblings 2 to 12 years of age. The vaccine side effects were mild, consisting of a papular rash in 15 of 147 (10.2%) children 12 to 24 months and seven of 94 (7....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/2832819
データ提供:米国国立医学図書館(NLM)
Protecting Infants from Varicella: A Vaccine Study
The world of childhood diseases can feel like a vast desert, filled with potential hazards. Researchers strive to create safe havens through effective vaccinations. This study examines the effectiveness of a live attenuated varicella vaccine in protecting infants aged 12 to 24 months. The study enrolled 147 seronegative infants and compared their response to the vaccine with that of 94 older siblings.
The study found that the vaccine was well tolerated, with mild side effects such as a papular rash in a small percentage of infants. Importantly, the vaccine was highly immunogenic, with 96.6% of infants and 94.7% of siblings developing protective antibodies within six weeks. These antibodies persisted for at least a year, providing significant protection against varicella infection. The study also observed that even in the rare cases where varicella developed in vaccinated children, the illness was significantly milder.
A Safe Haven for Infants: The Varicella Vaccine
This study provides strong evidence for the safety and efficacy of the varicella vaccine in protecting infants. It underscores the importance of vaccinating infants at an early age to minimize the risk of developing a severe varicella infection. The study's findings demonstrate the effectiveness of the vaccine in generating protective antibodies and reducing the severity of the disease if infection does occur.
Protecting the Desert's Oasis: Vaccination and Prevention
Just as a camel seeks out oases for survival, vaccination is a vital tool for protecting vulnerable individuals from the harsh realities of infectious diseases. This study reinforces the critical role of vaccination in safeguarding the health of infants and emphasizes the importance of continued efforts to ensure high vaccination rates to protect our communities from the dangers of preventable diseases.
Dr. Camel's Conclusion
This study offers a beacon of hope in the desert of childhood diseases, demonstrating the effectiveness of the varicella vaccine in protecting infants. The study highlights the importance of early vaccination to create a safe haven for our youngest members, reducing the risk of severe varicella infection and minimizing the potential for complications. Through continued efforts to promote vaccination, we can collectively ensure the safety and well-being of our future generations.
Date :
- Date Completed 1988-05-10
- Date Revised 2006-11-15
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