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Dopamine antagonists for treatment resistance in autism spectrum disorders: review and focus on BDNF stimulators loxapine and amitriptyline.
Author: ArnoldL Eugene, HanJoan C, HellingsJessica A
Original Abstract of the Article :
Drug development and repurposing are urgently needed for individuals with autism spectrum disorders (ASD) and psychiatric comorbidity, which often presents as aggression and self-injury. Areas covered: We review dopamine antagonists, including classical and atypical, as well as unconventional antips...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元:
https://doi.org/10.1080/14656566.2017.1308483
データ提供:米国国立医学図書館(NLM)
Dopamine Antagonists: A New Path for Treating Autism Spectrum Disorders
The world of autism spectrum disorders (ASD) is complex and challenging, and finding effective treatments remains a priority. This research examines the potential of dopamine antagonists, a class of drugs that block the action of dopamine in the brain, to address the behavioral challenges often associated with ASD. The study focuses on two dopamine antagonists, loxapine and amitriptyline, that have shown promise in preliminary studies, particularly in stimulating brain-derived neurotrophic factor (BDNF), a protein essential for brain development and function.
Dopamine Antagonists: A Potential for Behavioral Improvement
The study explores the potential of dopamine antagonists, specifically loxapine and amitriptyline, to improve behavioral challenges in individuals with ASD. These drugs, known for their effects on dopamine, have shown promising results in preliminary studies and might offer a new avenue for treating ASD. The authors highlight the potential of these medications to stimulate BDNF, a protein crucial for brain development and function, which could play a significant role in improving behavioral symptoms in ASD.
Dopamine Antagonists: A New Hope for ASD Treatment
This research suggests that dopamine antagonists could offer a novel approach to treating behavioral challenges associated with ASD. The study's findings provide a promising starting point for further research into these medications and their potential to enhance the lives of individuals with ASD. This is a fascinating area of research that could lead to new and effective treatments for this complex condition.
Dr.Camel's Conclusion
This research is a beacon of hope in the ongoing quest to understand and treat ASD. The potential of dopamine antagonists, particularly loxapine and amitriptyline, to improve behavioral challenges and stimulate BDNF opens up exciting possibilities for the future of ASD treatment. This is a step forward in our understanding of the complex neurobiology of ASD, and it underscores the importance of continued research into new treatment approaches.
Date :
- Date Completed 2017-04-17
- Date Revised 2018-12-02
Further Info :
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