Immunogenicity and safety of a novel MMR vaccine (live, freeze-dried) containing the Edmonston-Zagreb measles strain, the Hoshino mumps strain, and the RA 27/3 rubella strain: Results of a randomized, comparative, active controlled phase III clinical trial.

Author: BabuT Ramesh, GlueckReinhard, GuptaGaurav, JoshiHimanshu Arvind, MahapatroSamarendra, MitraMonjori, MittalRavindra, NayakUma Siddhartha, SanmukhaniJayesh, SiddaiahPrashanth, SoodAshwani

Paper Details 
Original Abstract of the Article :
This phase III clinical trial was conducted to evaluate the immunogenicity and safety of the single-dose and multi-dose formulations of a novel MMR vaccine (live, freeze-dried) developed by M/s Cadila Healthcare Limited, India (Cadila MMR vaccine), containing the Hoshino mumps strain, compared to th...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512778/

データ提供:米国国立医学図書館(NLM)

Immunogenicity and Safety of a Novel MMR Vaccine

This phase III clinical trial evaluated the immunogenicity and safety of a novel MMR vaccine developed by Cadila Healthcare Limited, India. The trial compared the immunogenicity of the Cadila MMR vaccine to that of an existing MMR vaccine developed by Serum Institute of India Limited, India. The study found that the novel Cadila MMR vaccine, containing the Hoshino mumps strain, was non-inferior to the existing Serum MMR vaccine in terms of antibody responses to measles, mumps, and rubella. Both vaccines were well tolerated by study participants.

A New Generation of MMR Vaccines

This research explores the development and evaluation of a novel MMR vaccine, representing a step forward in vaccine technology. Imagine a vast desert, where a new oasis emerges, offering a more effective and safe approach to preventing infectious diseases. The development of this novel MMR vaccine, like the discovery of a refreshing spring in the desert, signifies a significant advancement in public health.

Protecting Communities Through Vaccination

This study emphasizes the crucial role of vaccination in safeguarding public health. Just as a desert traveler relies on a reliable map and compass to navigate the vast landscape, we must rely on vaccines to protect ourselves and our communities from the threats of infectious diseases. This research reinforces the importance of ongoing vaccine development and evaluation to ensure optimal protection for all.

Dr.Camel's Conclusion

This clinical trial, like a caravan crossing a vast desert, demonstrates the effectiveness and safety of a novel MMR vaccine. The findings highlight the importance of continuous innovation and research in the development of vaccines, ensuring that we have the tools necessary to protect ourselves and our communities from the ever-present threat of infectious diseases.

Date :
  1. Date Completed 2018-03-14
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28362563

DOI: Digital Object Identifier

PMC5512778

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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