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A proof-of-concept investigation into ketamine as a pharmacological treatment for alcohol dependence: study protocol for a randomised controlled trial.

Author: BrandnerBrigitta, LawnWill, McAndrewAmy, MorganCelia J A, PorffyLilla, StevensTobias

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This non-commercial proof-of-concept trial aimed to assess the effectiveness of a combined repeated ketamine and psychological therapy program for reducing relapse in severe alcohol use disorder.
Paper Details　
Original Abstract of the Article :
Worldwide, alcohol abuse is a burgeoning problem. Abstinence is key to allow recovery of physical and mental health as well as quality of life, but treatment for alcohol dependence is associated with high relapse rates. Preliminary data have suggested that a combined repeated ketamine and psychologi...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379743/

データ提供：米国国立医学図書館（NLM）

Ketamine for Alcohol Dependence: A New Path in the Desert of Addiction

Alcohol abuse is a major public health concern, and treatment for alcohol dependence is often challenging. This study proposes a proof-of-concept investigation into the potential of ketamine as a pharmacological treatment for alcohol dependence. The researchers plan to conduct a randomized controlled trial to assess the effectiveness of a combined repeated ketamine and psychological therapy program in reducing relapse rates in severe alcohol use disorder. This study explores a novel approach to treating alcohol dependence, aiming to improve outcomes for those struggling with this condition.

A Promising New Approach to Alcohol Dependence: A Beacon in the Desert

This study offers a promising new approach to treating alcohol dependence. The researchers' proposed investigation into the potential benefits of ketamine, coupled with psychological therapy, represents a potential breakthrough in the fight against alcohol addiction. This research holds hope for improving the lives of those struggling with alcohol use disorder and reducing the devastating consequences of this condition.

Navigating the Desert of Addiction

The desert of addiction can be a difficult and dangerous place to navigate. This study offers a glimmer of hope in the search for effective treatments for alcohol dependence. The researchers' proposed investigation into the potential benefits of ketamine, coupled with psychological therapy, represents a potential breakthrough in the fight against this challenging condition. This research highlights the ongoing efforts to find innovative solutions for those struggling with addiction and to provide them with the support they need to recover.

Dr.Camel's Conclusion

This study offers a promising new approach to treating alcohol dependence. The researchers' proposed investigation into the potential benefits of ketamine, coupled with psychological therapy, represents a potential breakthrough in the fight against this challenging condition. This research holds hope for improving the lives of those struggling with alcohol use disorder and reducing the devastating consequences of this condition.

Date :
  1. Date Completed 2018-02-20
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

28372596

DOI: Digital Object Identifier

PMC5379743

Related Literature

Article Analysis
・Effective treatment of alcohol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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