Minocycline-Induced Hyperpigmentation in a Patient Treated with Erlotinib for Non-Small Cell Lung Adenocarcinoma.

Author: BellAnn T, BrzezniakChristina E, GratrixMax L, RomanJohn W

Paper Details 
Original Abstract of the Article :
While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxyc...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346923/

データ提供:米国国立医学図書館(NLM)

Minocycline and Skin Reactions in Lung Cancer Patients

This research explores the exciting world of epidermal growth factor receptor (EGFR) inhibitors, which have revolutionized the treatment of non-small cell lung cancer (NSCLC). It's like discovering a new oasis in the vast desert of cancer treatment! However, these inhibitors can sometimes lead to a pesky side effect: papulopustular skin eruption. It's like a sandstorm that pops up unexpectedly! To combat this, doctors often prescribe oral minocycline or doxycycline, which act like soothing sand-dunes to calm the eruption.

Minocycline: A Double-Edged Sword?

This study discovered a fascinating phenomenon: Minocycline itself can sometimes cause hyperpigmentation. Imagine a beautiful, vibrant landscape suddenly being painted with shades of brown. This is the unexpected side effect of minocycline, a medication that often helps with skin reactions. It's like the sandstorm subsiding, only to reveal a landscape that's changed in unexpected ways.

Navigating the Desert of Side Effects

This research highlights the complexity of treating lung cancer. While EGFR inhibitors offer hope, they can also lead to unexpected side effects. The journey through cancer treatment is like navigating a vast desert, with its own unique challenges and rewards. Doctors must carefully weigh the benefits of these powerful drugs against potential side effects like hyperpigmentation.

Dr.Camel's Conclusion

This research reminds us that even the most promising discoveries in medicine can come with unforeseen consequences. It is essential to consider all aspects of a treatment, including potential side effects, before embarking on a therapeutic journey. Just like an explorer in the desert, we must carefully consider the potential risks and benefits of every step we take.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

28413391

DOI: Digital Object Identifier

PMC5346923

Related Literature

SNS
PICO Info
in preparation
Languages

English

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