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The Effects of Tamoxifen on Plasma Lipoprotein(a) Concentrations: Systematic Review and Meta-Analysis.

Author: , BanachMaciej, GurbanCamelia, JonesSteven R, KostnerKaram, KotaniKazuhiko, LippiGiuseppe, PensonPeter, RizzoManfredi, RyszJacek, SahebkarAmirhossein, SerbanMaria-Corina, TothPeter P, UrsoniuSorin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Tamoxifen treatment was associated with a significant reduction in lipoprotein(a) [Lp(a)] levels.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Tamoxifen is a selective estrogen receptor modulator widely used in the treatment of breast cancer. Tamoxifen therapy is associated with lower circulating low-density lipoprotein cholesterol and increased triglycerides, but its effects on other lipids are less well studied. AIMS: We a...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501893/

データ提供：米国国立医学図書館（NLM）

Tamoxifen: A Shifting Sands of Lipid Levels

Tamoxifen, a drug commonly used in breast cancer treatment, is like a desert wind, subtly influencing the landscape of lipid levels. This research, like a team of scientists studying the effects of desert winds, investigates the impact of tamoxifen on lipoprotein(a) [Lp(a)] levels. The researchers conducted a meta-analysis, combining the findings of multiple studies to assess the overall effect of tamoxifen on Lp(a).

Tamoxifen's Impact on Lipid Levels

The meta-analysis revealed a statistically significant reduction in Lp(a) levels following tamoxifen treatment. It's like observing the desert sand dunes being reshaped by the wind, with tamoxifen acting as a force influencing lipid levels. This finding provides valuable insights into the potential effects of tamoxifen on cardiovascular health.

Navigating Tamoxifen Therapy with Awareness

This research underscores the importance of carefully monitoring lipid levels during tamoxifen therapy. It's like keeping a watchful eye on the shifting sands of the desert, ensuring a safe and effective journey. This information empowers patients to work with their healthcare professionals to manage potential side effects and to optimize their overall health.

Dr.Camel's Conclusion

This research, like a journey through the desert of lipid metabolism, highlights the subtle but significant impact of tamoxifen on Lp(a) levels. It's a reminder that even seemingly minor changes can have a ripple effect on our overall health.

Date :
  1. Date Completed 2017-07-26
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28573436

DOI: Digital Object Identifier

PMC5501893

Related Literature

Article Analysis
・Effects of tamoxifen
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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