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Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns.
Author: CarterGlen P, HowdenBenjamin P, WilliamsonDeborah A
Original Abstract of the Article :
Bacterial skin infections represent some of the most common infectious diseases globally. Prevention and treatment of skin infections can involve application of a topical antimicrobial, which may be an antibiotic (such as mupirocin or fusidic acid) or an antiseptic (such as chlorhexidine or alcohol)...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475228/
データ提供:米国国立医学図書館(NLM)
Battling Bacteria on the Skin: Topical Antimicrobials and the Quest for Resistance
The skin is our first line of defense against the outside world, like a protective layer of sand dunes shielding a desert oasis. However, bacteria can sometimes breach this barrier, leading to skin infections. Topical antimicrobials, which are applied directly to the skin, are often used to treat these infections. But as with many medical interventions, the effectiveness of these agents can be challenged by the emergence of bacterial resistance. This study explores the current landscape of topical antibacterials and antiseptics, their mechanisms of action, and the growing threat of resistance.
The researchers delved into the world of topical antimicrobials, examining the effectiveness of antibiotics like mupirocin and fusidic acid, as well as antiseptics like chlorhexidine and alcohol. They highlighted the importance of evidence-based approaches to using these agents and cautioned against their indiscriminate use, as this can contribute to the rise of bacterial resistance. The study also explored newer and emerging agents, seeking to identify more effective and durable solutions.
Understanding the Battleground of Resistance
The study revealed the critical importance of understanding and managing bacterial resistance. The indiscriminate use of antimicrobials can create a breeding ground for resistant bacteria, making it increasingly difficult to treat infections effectively. The researchers emphasized the need for careful consideration of the appropriate use of topical agents and the development of new strategies to combat resistance.
Protecting Our Skin and Our Future
This research reminds us that the battle against bacterial infections is a complex and ongoing endeavor. By understanding the mechanisms of action of topical antimicrobials and the challenges posed by resistance, we can make informed decisions about their use and work towards developing more effective and sustainable solutions. As always, it is crucial to consult with a healthcare professional to discuss the best treatment options for your individual needs.
Dr.Camel's Conclusion
This study is a call to action for all of us to be mindful of antimicrobial resistance. Like the delicate balance of a desert ecosystem, the use of antimicrobials requires careful consideration to ensure their effectiveness and prevent unintended consequences. By working together, we can protect our skin and our future from the threat of resistant bacteria.
Date :
- Date Completed 2017-11-02
- Date Revised 2018-12-02
Further Info :
Related Literature
English
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