Pharmacokinetic drug evaluation of extended release lorcaserin for the treatment of obesity.

Author: DunhamMarissa W, HurrenKathryn M

Paper Details 
Original Abstract of the Article :
Lorcaserin is a serotonin 2C receptor antagonist that was FDA approved in 2012. Lorcaserin is recently available as an extended-release (ER) formulation for the treatment of obesity as an adjunct to lifestyle modification. Areas covered: The pharmacokinetics, pharmacodynamics, efficacy, and safety o...See full text at original site
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引用元:
https://doi.org/10.1080/17425255.2017.1344214

データ提供:米国国立医学図書館(NLM)

Lorcaserin for Obesity: A New Extended-Release Formulation

This study explores the potential of lorcaserin, a medication that targets the serotonin 2C receptor, for treating obesity. The study examines the pharmacokinetics, pharmacodynamics, efficacy, and safety of a new extended-release formulation of lorcaserin, comparing it to the immediate-release version. The research aims to assess the effectiveness of this new formulation as an adjunct to lifestyle modifications for weight management.

Extended-Release Lorcaserin: A Promise for Improved Adherence

The study suggests that the extended-release formulation of lorcaserin is bioequivalent to the immediate-release version, offering a simplified dosing regimen and potentially improving patient adherence. The research also indicates that lorcaserin, in both immediate and extended-release forms, can lead to modest weight loss, particularly in individuals with diabetes. However, it is crucial to note that while lorcaserin may provide benefits in terms of tolerability and ease of administration, it may not be as effective as other anti-obesity medications.

Navigating Weight Management: A Balanced Approach

The study highlights the ongoing search for effective and safe medications for treating obesity. While lorcaserin shows promise, it is essential to remember that weight management requires a multifaceted approach, combining lifestyle modifications, such as diet and exercise, with medication when appropriate.

Dr.Camel's Conclusion

This study delves into the world of weight management, exploring a new extended-release formulation of lorcaserin. The findings suggest that this new formulation holds potential for improved adherence and may offer a viable option for individuals seeking to manage their weight. However, it is crucial to remember that weight management is a complex journey that necessitates a holistic approach, combining medication with lifestyle changes.

Date :
  1. Date Completed 2017-08-07
  2. Date Revised 2017-08-07
Further Info :

Pubmed ID

28636828

DOI: Digital Object Identifier

10.1080/17425255.2017.1344214

Related Literature

SNS
PICO Info
in preparation
Languages

English

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