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Nonclinical Development of ENV905 (Difluprednate) Ophthalmic Implant for the Treatment of Inflammation and Pain Associated with Ocular Surgery.

Author: CulpDavid, GarciaAndres, GilgerBrian C, HammLee, NavratilTomas, RobesonRiLee, StrubleCraig, VerhoevenRozemarijn S, YerxaBenjamin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the efficacy and pharmacokinetics of ENV905 (difluprednate or DFBA) Ophthalmic Implant, a single-dose drug delivery system, compared to 0.05% Durezol, a topical corticosteroid. The study found that ENV905 was as effective as Durezol in reducing inflammation and pain after ocular surgery and that it had a longer duration of action.
Paper Details　
Original Abstract of the Article :
Topical corticosteroids are widely used in the treatment of inflammation and pain after ocular surgery, but they possess several shortcomings, including frequent dosing and low patient adherence. We evaluated the efficacy and pharmacokinetics of ENV905 (difluprednate or DFBA) Ophthalmic Implant, a s...See full text at original site
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引用元：
https://doi.org/10.1089/jop.2016.0195

データ提供：米国国立医学図書館（NLM）

Nonclinical Development of ENV905 (Difluprednate) Ophthalmic Implant for the Treatment of Inflammation and Pain Associated with Ocular Surgery

The field of [Ophthalmology] is constantly evolving, with new technologies and treatments being developed to improve patient outcomes. This research delves into the potential benefits of [ENV905 (difluprednate or DFBA) Ophthalmic Implant] in managing [Inflammation and pain] following [Ocular surgery]. The study compares the efficacy and pharmacokinetics of this single-dose drug delivery system with [0.05% Durezol], a commonly used topical corticosteroid. The findings offer valuable insights into the potential advantages of this novel approach in managing [Post-operative inflammation and pain] in patients undergoing [Ocular surgery].

A New Approach to Ocular Pain Relief

The study demonstrates that [ENV905 Ophthalmic Implant] shows promising results in [Reducing inflammation and pain] after [Ocular surgery], suggesting it could be a more convenient and effective alternative to [Frequent topical corticosteroid applications]. This innovative approach could potentially enhance patient comfort and improve compliance with post-operative medication regimens.

Navigating the Sands of Ocular Surgery

This research highlights the importance of [Exploring new drug delivery systems] to address challenges associated with traditional treatments. The findings suggest that [ENV905 Ophthalmic Implant] could offer a more convenient and effective option for managing [Post-operative inflammation and pain]. This innovative approach could potentially improve patient outcomes and enhance their overall recovery experience.

Dr. Camel's Conclusion

Just as a camel uses its vision to navigate the vast desert, advances in [Ophthalmology] are continuously improving our vision and overall health. This research highlights the potential of [Innovative drug delivery systems] to provide more effective and convenient treatment options for patients. The development of [ENV905 Ophthalmic Implant] could lead to a brighter future for those undergoing [Ocular surgery].

Date :
  1. Date Completed 2019-10-28
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

28650720

DOI: Digital Object Identifier

10.1089/jop.2016.0195

Related Literature

Article Analysis
・Effects of difluprednate ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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