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The Effects of Switching to Vonoprazan, a Novel Potassium-Competitive Acid Blocker, on Gastric Acidity and Reflux Patterns in Patients with Erosive Esophagitis Refractory to Proton Pump Inhibitors.
Author: EguchiTakaaki, FujitaMikio, HashimuraHiroki, KanamoriAtsushi, KanoChise, MatsumotoKei, MomoseKenji, ObataDaisuke, OkadaAkihiko, TsujimaeMasahiro, YamashitaHiroshi, YoshizakiTetsuya
Original Abstract of the Article :
BACKGROUND/AIM: The effects of vonoprazan and proton pump inhibitors (PPIs) in patients with reflux esophagitis (RE) have not yet been compared using multichannel intraluminal impedance-pH (MII-pH). METHODS: A total of 8 patients with persistent gastric mucosal injury, despite completing an 8-week ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000478255
データ提供:米国国立医学図書館(NLM)
Vonoprazan: A New Hope for Reflux Esophagitis
[Reflux esophagitis] can be a real pain, literally! This study explores the effectiveness of [vonoprazan], a new drug, in treating patients who haven't responded well to traditional medications like [proton pump inhibitors (PPIs)]. The researchers used [multichannel intraluminal impedance-pH (MII-pH)] to measure the effects of vonoprazan on gastric acidity and reflux patterns. The results suggest that vonoprazan could be a promising treatment option for those struggling with [PPI-refractory reflux esophagitis].
Vonoprazan: A Potential Solution for Resistant Reflux
Vonoprazan, like a skilled desert traveler equipped with a water-finding stick, can effectively manage gastric acidity and reflux. The study found that vonoprazan significantly increased gastric pH and reduced acid reflux events in patients with [PPI-refractory reflux esophagitis]. This offers a beacon of hope for patients who haven't found relief with traditional treatments.
Vonoprazan: A New Era in Reflux Treatment
This study, like a refreshing oasis in the desert of reflux treatment, suggests that vonoprazan could be a valuable tool in managing this condition. It's a promising development for patients seeking effective and durable relief from their symptoms.
Dr.Camel's Conclusion
This research is like a desert expedition, revealing the potential of vonoprazan as a new and effective treatment for [PPI-refractory reflux esophagitis]. The findings offer hope for patients who haven't found relief with traditional medications and highlight the importance of ongoing research in developing new therapeutic strategies.
Date :
- Date Completed 2018-04-30
- Date Revised 2022-03-21
Further Info :
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