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The Role of Radical Prostatectomy and Radiotherapy in Treatment of Locally Advanced Prostate Cancer: A Systematic Review and Meta-Analysis.

Author: FahmyOmar, GakisGeorgios, HadiSyed H S M, Khairul-AsriMohd Ghani, StenzlArnulf

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Radical prostatectomy plus adjuvant radiotherapy resulted in improved outcomes in advanced prostate cancer compared to radical prostatectomy alone.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The role of radical prostatectomy (RP) is still controversial for locally advanced prostate cancer (PC). Radiotherapy (RT) and hormonal therapy (HT) are usually used as a primary treatment. MATERIAL AND METHODS: A systematic online search was conducted according to Preferred Reporting I...See full text at original site
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引用元：
https://doi.org/10.1159/000478789

データ提供：米国国立医学図書館（NLM）

Navigating the Treatment of Advanced Prostate Cancer

Prostate cancer, a formidable foe, can often be likened to a towering sand dune in the desert, challenging even the most experienced traveler. When the cancer spreads beyond the prostate gland (locally advanced prostate cancer), the treatment options become more complex, requiring a multifaceted approach like a skilled traveler navigating a treacherous landscape. This systematic review and meta-analysis aimed to shed light on the effectiveness of radical prostatectomy (RP), radiotherapy (RT), and hormonal therapy (HT) in managing this challenging condition.

A Comprehensive Guide to Treatment Strategies

The study analyzed data from 14 studies encompassing over 17,000 patients with locally advanced prostate cancer. The results showed that RP, RT, and HT, used individually or in combination, could all contribute to extending survival time. The study's findings are akin to a well-crafted map, offering guidance for clinicians and patients seeking effective strategies to combat this aggressive disease. The researchers found that RP and RT often played a crucial role in improving survival outcomes, particularly when combined with other treatments.

Empowering Patients with Knowledge

This research provides valuable insights into the treatment options for locally advanced prostate cancer, empowering patients to make informed decisions about their healthcare. Like a seasoned desert explorer equipped with a compass and map, patients can navigate the complexities of their condition with greater confidence. This study highlights the importance of a multidisciplinary approach to treatment, a strategy that can help patients effectively manage their disease and potentially achieve favorable outcomes.

Dr.Camel's Conclusion

This comprehensive review offers a valuable guide for navigating the treatment of locally advanced prostate cancer, a journey as challenging as traversing a vast desert. The study highlights the importance of a multidisciplinary approach and provides critical information for patients to make informed decisions about their healthcare, ensuring the best possible outcomes in this challenging battle.
Date :
  1. Date Completed 2018-06-18
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

28675891

DOI: Digital Object Identifier

10.1159/000478789

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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