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Azodisal sodium in the treatment of ulcerative colitis. A study of tolerance and relapse-prevention properties.

Author: JärnerotG, KraazW, Sandberg-GertzénH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Azodisal sodium was well tolerated by more than 80% of patients with ulcerative colitis who were intolerant to sulfasalazine, but 12.5% of patients stopped taking the drug due to diarrhea. Azodisal sodium was effective in maintaining remission in patients with ulcerative colitis.
Paper Details　
Original Abstract of the Article :
One hundred sixty patients intolerant of or allergic to sulfasalazine (Salazopyrin, Azulfidine) participated in an open tolerance study of azodisal sodium (Dipentum). More than 4 of every 5 patients tolerated azodisal sodium well, but 12.5% of patients stopped medication because of diarrhea. Even af...See full text at original site
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引用元：
https://doi.org/10.1016/0016-5085(86)90882-6

データ提供：米国国立医学図書館（NLM）

Azodisal Sodium: A Potential Treatment for Ulcerative Colitis

Ulcerative colitis, an inflammatory bowel disease characterized by chronic inflammation of the colon, can cause significant pain, discomfort, and complications. This study examines the potential of azodisal sodium, a derivative of sulfasalazine, as a treatment for ulcerative colitis. The researchers conducted two studies, one to assess tolerance and the other to evaluate relapse-prevention properties. Their findings suggest that azodisal sodium may be a viable alternative for patients who cannot tolerate sulfasalazine, demonstrating good tolerance and effectiveness in maintaining remission in patients with ulcerative colitis.

Azodisal Sodium: A Potential Solution for Sulfa-Intolerant Patients

This study offers a ray of hope for individuals with ulcerative colitis who cannot tolerate sulfasalazine. Just as a desert traveler seeks an alternative route when faced with a blocked path, patients with ulcerative colitis may find relief in azodisal sodium. The study's findings highlight the potential of this medication as a safe and effective treatment option for patients who cannot tolerate sulfasalazine.

Navigating the Terrain of Ulcerative Colitis: Finding the Right Treatment

This study underscores the importance of individualized treatment approaches for ulcerative colitis. Just as a desert traveler adapts their journey to the unique terrain, clinicians must tailor treatment strategies to meet the individual needs of each patient. The study's findings emphasize the importance of considering alternative treatments for patients who do not respond well to conventional therapies.

Dr.Camel's Conclusion

This research highlights the ongoing search for effective treatments for inflammatory bowel diseases. Just as a camel's survival depends on its ability to adapt to the changing desert environment, individuals with inflammatory bowel diseases require personalized care and access to a range of treatment options.

Date :
  1. Date Completed 1986-04-02
  2. Date Revised 2019-07-07
Further Info :

Pubmed ID

2868964

DOI: Digital Object Identifier

10.1016/0016-5085(86)90882-6

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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