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Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial.
Author: BigelowGeorge E, DunnKelly E, StrainEric C, TompkinsD Andrew
Original Abstract of the Article :
IMPORTANCE: Opioid use disorder (OUD) is a significant public health problem. Supervised withdrawal (ie, detoxification) from opioids using clonidine or buprenorphine hydrochloride is a widely used treatment. OBJECTIVE: To evaluate whether tramadol hydrochloride extended-release (ER), an approved a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710234/
データ提供:米国国立医学図書館(NLM)
Tramadol Extended-Release: A New Oasis in the Desert of Opioid Withdrawal?
Opioid use disorder (OUD) is a complex and often debilitating condition. The process of withdrawing from opioids can be a challenging experience, marked by unpleasant symptoms and a high risk of relapse. The research team behind this study wanted to explore the potential of tramadol hydrochloride extended-release (ER), a medication with both opioid and non-opioid mechanisms of action, as a treatment for supervised withdrawal from opioids. They conducted a randomized clinical trial, comparing tramadol ER to clonidine and buprenorphine, two commonly used medications for opioid withdrawal. The results are intriguing! Tramadol ER demonstrated similar effectiveness to buprenorphine in reducing opioid withdrawal symptoms and was more effective than clonidine in managing these symptoms during a residential tapering program. The study also found that tramadol ER was well-tolerated and did not lead to significant increases in the use of other medications, which is an important consideration for individuals with complex medical needs. The researchers emphasize the need for further investigation to fully understand the long-term efficacy and safety of tramadol ER for managing opioid withdrawal.
Tramadol ER: A Potential New Pathway for Opioid Withdrawal
This study provides a hopeful glimpse into the potential of tramadol ER for managing opioid withdrawal. It seems to be a viable alternative to traditional medications, offering comparable effectiveness with fewer side effects. This is particularly promising for individuals seeking a less burdensome withdrawal experience. However, it’s essential to note that the study focused on supervised withdrawal settings, and further research is needed to explore the effectiveness of tramadol ER in different contexts. This research reminds us that navigating the desert of opioid withdrawal requires a multi-faceted approach, and finding the right treatment strategy for each individual is key.
Navigating the Terrain of Opioid Withdrawal
The complexity of OUD demands a variety of treatment approaches. This study suggests that tramadol ER might be a promising addition to the toolkit for managing opioid withdrawal. It's important to remember that the effectiveness of any treatment can vary depending on individual factors. Always consult with a healthcare professional to discuss your options and create a personalized treatment plan that addresses your specific needs.
Dr.Camel's Conclusion
This research suggests that tramadol ER could be a valuable alternative for those seeking to navigate the desert of opioid withdrawal. It shows promise in managing withdrawal symptoms with fewer potential side effects. However, further research is needed to fully understand its long-term benefits and ensure its safe and effective use across various settings.
Date :
- Date Completed 2017-09-26
- Date Revised 2019-02-05
Further Info :
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