Week 96 results of the randomized, multicentre Maraviroc Switch (MARCH) study.

Author: , Alberto ArnaizJ, AminJ, Andrade-VillanuevaJ, BellosoW, ClarkA, ClarkeA, CooperD, EmeryS, GatellJ, GillJ, HarriganR, HorbanA, KaiserR, KelleherA, LossoM, MaderoJ S, MallonP, PettS L, PorteiroN, PrazuckT, RockstrohJ K, RuxrungthamK, SilkD, SugiuraW, TuE, WolffM, WoolleyI

Paper Details 
Original Abstract of the Article :
The Maraviroc Switch (MARCH) study week 48 data demonstrated that maraviroc, a chemokine receptor-5 (CCR5) inhibitor, was a safe and effective switch for the ritonavir-boosted protease inhibitor (PI/r) component of a two nucleos(t)ide reverse transcriptase inhibitor [N(t)RTI] plus PI/r-based antiret...See full text at original site
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引用元:
https://doi.org/10.1111/hiv.12532

データ提供:米国国立医学図書館(NLM)

Durability of Maraviroc Switch for HIV Treatment

This research investigates the effectiveness of maraviroc, a medication used to treat HIV, as a switch therapy for patients already on a protease inhibitor-based regimen. Like a seasoned explorer navigating a vast desert, the researchers are seeking a safe and effective route to manage this complex disease.

The study found that maraviroc was a safe and effective switch for the protease inhibitor component of a two-drug HIV regimen in patients with R5-tropic virus. This finding was confirmed at week 96, demonstrating the durability of this therapeutic approach.

These findings offer valuable insights into the management of HIV and provide a promising therapeutic option for patients who may benefit from a switch to maraviroc.

A New Route in the Desert of HIV

This study offers a new and promising route in the desert of HIV treatment, demonstrating the effectiveness of maraviroc as a safe and durable switch therapy. This approach provides hope for patients seeking alternative treatment options.

Living a Healthy Life with HIV

It's important to remember that HIV treatment requires a holistic approach, encompassing both medication and lifestyle modifications. Just as a camel needs to adapt to the harsh desert environment, patients with HIV need to make adjustments to their lives to ensure optimal health and well-being.

Dr.Camel's Conclusion

This study provides valuable evidence for the effectiveness of maraviroc as a switch therapy for HIV, offering a new path in the ongoing battle against this complex disease.

Date :
  1. Date Completed 2018-07-10
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28703491

DOI: Digital Object Identifier

10.1111/hiv.12532

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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